2-(Ethoxycarbonyl)-N-methylindole CAS 18450-24-3

Purity 97%+In StockPharmaceutical Standards
CAS No.18450-24-3
Molecular FormulaC12H21NO2
Molecular Weight211.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Ethoxycarbonyl)-N-methylindole CAS 18450-24-3 chemical structure

Description

The occurrence of 2-(Ethoxycarbonyl)-N-methylindole is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 2-(Ethoxycarbonyl)-N-methylindole (CAS 18450-24-3), a certified reference material (molecular formula C12H21NO2, MW 211.30 g/mol) for analytical method development and quality control.

The molecular framework of 2-(Ethoxycarbonyl)-N-methylindole (C12H21NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Ethoxycarbonyl)-N-methylindole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H21NO2
Molecular Weight211.30 g/mol
AppearanceWhite to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1962
Nitrogen Atoms1

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