5-Chloro-7-nitroquinolin-8-ol CAS 18472-03-2
| CAS No. | 18472-03-2 |
| Molecular Formula | C9H5ClN2O3 |
| Molecular Weight | 224.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5-Chloro-7-nitroquinolin-8-ol (CAS 18472-03-2), a certified reference material (molecular formula C9H5ClN2O3, MW 224.60 g/mol) for analytical method development and quality control.
Structurally, 5-Chloro-7-nitroquinolin-8-ol (C9H5ClN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 224.60 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 5-Chloro-7-nitroquinolin-8-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H5ClN2O3 |
| Molecular Weight | 224.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 1-(2-Chloro-6-nitrophenyl)-1H-1,2,4-triazole (CAS 1018053-08-1)
- 6-Chloro-3-nitroquinolin-4-ol (CAS 101861-61-4)
- 8-Chloro-2-oxo-2H-chromene-3-carboxylic acid (CAS 107747-67-1)
- 2-Chloro-7-nitroquinazolin-4-amine (CAS 1107694-81-4)
- [(3-chloro-4-cyanophenyl)carbamoyl]formic acid (CAS 1153559-74-0)
- 2-Chloro-5-nitro-1H-indole-3-carbaldehyde (CAS 117752-76-8)
- 2-Chloro-6-nitroquinazolin-4-amine (CAS 1279870-95-9)
- 2-Chloro-3-nitroquinolin-4-ol (CAS 1314946-36-5)
Recommended Standards
- 4-Chloro-3-nitroquinolin-2(1H)-one (CAS 172469-73-7)
- 7-Chloro-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid (CAS 187231-22-7)
- 7-Nitro-1H-indole-2-carbonyl chloride (CAS 1706430-07-0)
- 5-(4-Chlorophenyl)-1,3,4-oxadiazole-2-carboxylic acid (CAS 187999-13-9)
- Chroman-6-ylmethanamine hydrochloride (CAS 1255718-26-3)
- S-Ethylglutathione (CAS 24425-52-3)
- (5-Isobutyl-1-phenyl-1H-pyrazol-3-yl)methanamine (CAS 1220348-66-2)
- Trifluoromethoxy-acetonitrile (CAS 1301739-28-5)
- 2-Ethyl-3-methoxybenzonitrile (CAS 102236-67-9)
- 3-(1H-imidazol-5-yl)picolinic acid (CAS 774485-69-7)
- 2-(Aminomethyl)benzofuran-7-amine (CAS 165737-01-9)
- Sodium 6-ethoxy-1,3-benzothiazole-2-carboxylate (CAS 1785761-75-2)
- N-(4-Chlorophenyl)-N-(methylsulfonyl)alanine (CAS 1008074-24-5)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
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