7-Amino-5-fluoroquinolin-8-ol CAS 18472-07-6
| CAS No. | 18472-07-6 |
| Molecular Formula | C9H7FN2O |
| Molecular Weight | 178.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-Amino-5-fluoroquinolin-8-ol (CAS 18472-07-6) is a high-purity analytical reference standard with the molecular formula C9H7FN2O and a molecular weight of 178.16 g/mol.
7-Amino-5-fluoroquinolin-8-ol (C9H7FN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H7FN2O |
| Molecular Weight | 178.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 3-Amino-6-fluoroquinolin-4-ol (CAS 1027512-05-5)
- 7-AMINO-4-FLUORO-1(2H)-ISOQUINOLINONE (CAS 1036390-58-5)
- 5-Amino-3-(2-fluorophenyl)isoxazole (CAS 119162-49-1)
- 5-Amino-3-(3-fluorophenyl)isoxazole (CAS 119162-50-4)
- 2-Amino-6-fluoroquinolin-3-ol (CAS 2435612-57-8)
- 3-Amino-6-fluoroquinolin-4(1H)-one (CAS 866472-96-0)
- 5-Amino-3-(4-fluorophenyl)isoxazole (CAS 81465-82-9)
- 5-Amino-6-fluoroquinolin-2(1H)-one (CAS 950520-27-1)
Recommended Standards
- 4-fluoronaphthalene-1,6-diol (CAS 1824496-31-2)
- 2,2-Difluoro-2-(1,3-thiazol-2-yl)acetamide (CAS 1850835-10-7)
- 5-(2-Fluorophenyl)-3-methyl-1,2,4-oxadiazole (CAS 1820747-54-3)
- 2-(Difluoromethyl)thiophene-3-carboxylic acid (CAS 189330-26-5)
- 2-(2,2,2-Trifluoroethyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 2551120-16-0)
- Neopentyl Methanthiosulfonate (CAS 190852-37-0)
- 2-Chloro-5-(pentafluoroethyl)thiophene (CAS 1429056-29-0)
- methyl 2-(chlorosulfonyl)propanoate (CAS 20449-10-9)
- Darolutamide Impurity 17 (CAS CATO-C4X-310617)
- Bis(2-isopropylphenyl) Phenyl Phosphate (CAS 69500-29-4)
- 2-{[(tert-butoxy)carbonyl](propyl)amino}propanoic acid (CAS 1347875-15-3)
- 2-(((Dimethyl(oxo)-lambda6-sulfanylidene)amino)methyl)benzoic acid (CAS 1621962-44-4)
- 2-Hydroxy-6-methylcyclohexa-2,5-diene-1,4-dione (CAS 2446-75-5)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
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