(-)-Α-Ethyl-3,5-bis(trifluoromethyl)benzenemethanol CAS 184888-50-4
| CAS No. | 184888-50-4 |
| Molecular Formula | C11H10F6O |
| Molecular Weight | 272.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(-)-Α-Ethyl-3,5-bis(trifluoromethyl)benzenemethanol (CAS 184888-50-4), molecular formula C11H10F6O and molecular weight 272.19 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, (-)-Α-Ethyl-3,5-bis(trifluoromethyl)benzenemethanol is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 272.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (-)-Α-Ethyl-3,5-bis(trifluoromethyl)benzenemethanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10F6O |
| Molecular Weight | 272.19 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | F-containing |
Recommended Standards
- 1-Ethyl-2-methoxy-4,5-bis(trifluoromethyl)benzene (CAS 1805509-63-0)
- 3-chloroquinoline-5-sulfonyl chloride (CAS 1956366-76-9)
- (E)-4,4,5,5-Tetramethyl-2-(5-phenylpent-1-en-1-yl)-1,3,2-dioxaborolane (CAS 157945-84-1)
- 3-chloroquinoline-7-sulfonyl chloride (CAS 1956371-35-9)
- 1,2,3,4-Tetrahydroisoquinoline-7-carboxylic acid (CAS 160346-57-6)
- 1-(4-{2-[4-(Dibutylamino)Phenyl]Vinyl}Phenyl)-2,2,2-Trifluoroethanone (CAS 192190-91-3)
- 1-(bromomethyl)-2-(difluoromethoxy)-3-fluorobenzene (CAS 1261776-41-3)
- 7-(Difluoromethoxy)quinolin-2-ol (CAS 1261458-20-1)
- (4-Benzyl-1-piperazinyl)(2-piperidinyl)methanonehydrochloride (CAS 1236266-59-3)
- (R,R)Palonosetron HCl (CAS 135729-75-8)
- 2-(6-Methylpyridin-3-yl)piperidine-1-carbaldehyde (CAS 1352523-89-7)
- 2-(2-Iodo-4,5-dimethoxyphenyl)acetic acid (CAS 35323-09-2)
- (2R,3S)-Methyl 2-methoxytetrahydrofuran-3-carboxylate (CAS 143789-16-6)
- Allo-D-Ile12-Tirzepatide (CAS CATO-CPTD788963)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com