5-Chloro-2-fluoro-4-hydroxybenzonitrile CAS 1849382-33-7
| CAS No. | 1849382-33-7 |
| Molecular Formula | C7H3ClFNO |
| Molecular Weight | 171.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-2-fluoro-4-hydroxybenzonitrile is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Chloro-2-fluoro-4-hydroxybenzonitrile (CAS 1849382-33-7) is a high-purity analytical reference standard with the molecular formula C7H3ClFNO and a molecular weight of 171.56 g/mol.
Based on its molecular formula C7H3ClFNO, 5-Chloro-2-fluoro-4-hydroxybenzonitrile contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 171.56 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Chloro-2-fluoro-4-hydroxybenzonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H3ClFNO |
| Molecular Weight | 171.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-4-fluoro-1-isocyanatobenzene (CAS 1016788-39-8)
- 6-Chloro-8-fluoro-[1,2,4]triazolo[4,3-a]pyridine (CAS 1020253-21-7)
- 2-Chloro-4-fluorobenzoxazole (CAS 1163123-39-4)
- 4-Chloro-2-fluoro-7H-pyrrolo[2,3-d]pyrimidine (CAS 1206825-32-2)
- 6-Chloro-5-fluoro-1H-pyrazolo[3,4-b]pyridine 1256785-11-1 (CAS 1256785-11-1)
- 4-Chloro-7-fluoro-5H-pyrrolo[3,2-d]pyrimidine (CAS 1311275-30-5)
- 6-Chloro-3-fluoroimidazo[1,2-b]pyridazine (CAS 1315359-81-9)
- 3-Chloro-7-fluorobenzo[d]isoxazole (CAS 1352899-19-4)
Recommended Standards
- 2-Amino-6-chloro-5-fluoro-3-pyridinecarbonitrile (CAS 1820711-14-5)
- 6-Chloro-3-fluoro-2-hydroxybenzonitrile (CAS 1891204-17-3)
- 3-Chloro-5-fluorobenzisoxazole (CAS 178747-50-7)
- 7-Chloro-5-fluoro-1,3-benzoxazole (CAS 192582-98-2)
- Ethyl 3-chloro-6-methoxypicolinate (CAS 1001735-31-4)
- (R)-2-Amino-N-benzyl-N,3,3-trimethylbutanamide (CAS 1867654-07-6)
- Methyl 7-methoxybenzo[d]thiazole-2-carboxylate (CAS 1261563-40-9)
- 1-(4-Bromophenyl)-1h-1,2,3-triazole-5-carboxylic acid (CAS 20177-59-7)
- 6-(trifluoromethyl)-2,3-dihydrobenzofuran-3-ol (CAS 2708288-10-0)
- 1-Morpholino-2-(4-(4-(pyridin-2-yl)pyrimidin-2-yl)phenoxy)ethan-1-one (CAS 477870-55-6)
- 2-(But-2-yn-1-yl)cycloheptan-1-ol (CAS 1457716-55-0)
- 4-Chlorothiazole-5-carbonyl chloride (CAS 1133931-01-7)
- MEthyl (2R)-2-{[(benzyloxy)carbonyl]amino}-4-methylpentanoate (CAS 73397-22-5)
- Insulin Degludec Impurity 12 (CAS CATO-C4X-215712)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com