4-(Bromomethyl)-1-fluoro-2-(trifluoromethyl)benzene CAS 184970-26-1
| CAS No. | 184970-26-1 |
| Molecular Formula | C8H5BrF4 |
| Molecular Weight | 257.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Bromomethyl)-1-fluoro-2-(trifluoromethyl)benzene.
4-(Bromomethyl)-1-fluoro-2-(trifluoromethyl)benzene (CAS 184970-26-1) is a high-purity analytical reference standard with the molecular formula C8H5BrF4 and a molecular weight of 257.02 g/mol.
The molecular framework of 4-(Bromomethyl)-1-fluoro-2-(trifluoromethyl)benzene (C8H5BrF4) is characterized by fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5BrF4 |
| Molecular Weight | 257.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | F/Br-containing |
Related Bromomethyl Standards
- 2-(Bromomethyl)-4-fluoro-1-(trifluoromethyl)benzene (CAS 239135-48-9)
- 1-(bromomethyl)-2,3,5,6-tetrafluoro-4-methylbenzene 1-(bromomethyl)-2,3,5,6-tetrakis(fluoranyl)-4-methyl-benzene 92814-00-1 A844354 (CAS 92814-00-1)
- 6-(Bromomethyl)-2-(trifluoromethyl)pyrimidin-4-ol (CAS 1269293-23-3)
- 2-(Bromomethyl)-7-nitrobenzo[d]oxazole (CAS 1806303-39-8)
- 2-(Bromomethyl)-5-nitrobenzo[d]oxazole (CAS 1806341-88-7)
- 2-(Bromomethyl)-6-nitrobenzo[d]oxazole (CAS 1806555-89-4)
- 3-[4-(Bromomethyl)-3-fluorophenyl]-1,2,4-oxadiazole (CAS 1146699-64-0)
- 3-(Bromomethyl)-7-fluoroquinoxalin-2(1H)-one (CAS 2758642-34-9)
Recommended Standards
- 2-Fluoro-3-(trifluoromethyl)benzyl Bromide (CAS 184970-25-0)
- 1-Bromo-4-(1,2,2,2-tetrafluoroethyl)benzene (CAS 189762-23-0)
- 3,4-Dichloro-5-(difluoromethoxy)benzoic acid (CAS 1807058-88-3)
- 1-(1-Bromo-2,2,2-trifluoroethyl)-4-fluorobenzene (CAS 81577-15-3)
- 5-Bromo-7-methoxybenzo[d]isoxazole (CAS 198280-98-7)
- 5-Bromo-4-methyl-2-(methylthio)pyridine (CAS 247135-44-0)
- N-(4-morpholinophenyl)-1-(4-propoxyphenyl)methanimine (CAS 866150-82-5)
- 1,3-Dimethyl-1-propoxyurea (CAS 502448-03-5)
- 5-((4,5-Dimethyl-2-nitrophenoxy)methyl)-1,3,4-oxadiazol-2-amine (CAS 1706458-70-9)
- 8-Ethyl-4-(2-methoxybenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326810-79-0)
- (S)-1-(4-(Difluoromethoxy)phenyl)ethan-1-amine hydrochloride (CAS 2045362-22-7)
- (R)-2-(1-Aminoethyl)-6-(trifluoromethyl)pyridin-4-amine (CAS 2641906-29-6)
- 3-Methylmorpholine-3-carboxylic acid hydrochloride (CAS 2055840-08-7)
- 141801-03-8 IL-1 Receptor Peptide (human) (CAS 141801-03-8)
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