4-Chloro-5-(trifluoromethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine CAS 1854086-23-9
| CAS No. | 1854086-23-9 |
| Molecular Formula | C7H4ClF3N4 |
| Molecular Weight | 236.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-Chloro-5-(trifluoromethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine (CAS 1854086-23-9), molecular formula C7H4ClF3N4 and molecular weight 236.58 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C7H4ClF3N4, 4-Chloro-5-(trifluoromethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 236.58 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 4-Chloro-5-(trifluoromethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4ClF3N4 |
| Molecular Weight | 236.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
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Recommended Standards
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