1-(2-Fluoroethyl)-3-((3,3,3-trifluoropropoxy)methyl)-1H-pyrazole CAS 1856031-94-1
| CAS No. | 1856031-94-1 |
| Molecular Formula | C9H12F4N2O |
| Molecular Weight | 240.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2-Fluoroethyl)-3-((3,3,3-trifluoropropoxy)methyl)-1H-pyrazole (CAS 1856031-94-1) is a high-purity analytical reference standard with the molecular formula C9H12F4N2O and a molecular weight of 240.20 g/mol.
The molecular framework of 1-(2-Fluoroethyl)-3-((3,3,3-trifluoropropoxy)methyl)-1H-pyrazole (C9H12F4N2O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H12F4N2O |
| Molecular Weight | 240.20 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoroethyl Standards
- 1-(2-Fluoroethyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1905405-89-1)
- 1-(2-Fluoroethyl)-4-iodo-1H-pyrazole (CAS 398152-63-1)
- 4-(2-Fluoroethyl)piperidin-4-yl 2,2,2-trifluoroacetate (CAS 2608050-07-1)
- 1-(2-fluoroethyl)-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1049730-39-3)
- 2-[(2-Fluoroethyl)sulfanyl]-5-methyl-1,3-benzothiazole (CAS 155559-65-2)
- 4-(4-(2-Fluoroethyl)piperazin-1-yl)-2-methoxyaniline (CAS 1807809-74-0)
- 1-(2-Fluoroethyl)-3-methyl-1H-pyrazole-4-sulfonyl chloride (CAS 1394021-33-0)
- 1-(2-Fluoroethyl)-4-iodo-3-methyl-1H-pyrazole (CAS 1443278-85-0)
Recommended Standards
- ethyl 2-amino-5-(trifluoromethyl)-1,3-thiazole-4-carboxylate (CAS 1820704-65-1)
- 4-Methyl-2-(methylsulfonyl)-6-(trifluoromethyl)pyrimidine (CAS 186357-34-6)
- methyl 3-methoxy-5-(trifluoromethyl)thiophene-2-carboxylate (CAS 181063-89-8)
- (4-((Trifluoromethyl)sulfonyl)phenyl)methanol (CAS 219872-98-7)
- 7-Chloro-8-iodo-6-(trifluoromethyl)quinazoline-2,4(1H,3H)-dione (CAS 2655729-07-8)
- CAS 2260670-33-3 (CAS 2260670-33-3)
- 2-Chloro-N-(3-((4-methyl-3-(morpholinosulfonyl)phenyl)amino)-3-oxopropyl)benzamide (CAS 869355-78-2)
- Methyl (2e)-3-(3,4-dichlorophenyl)prop-2-enoate (CAS 82475-75-0)
- (2Z)-2-(3-Chlorophenyl)-3-[2-(4-chlorophenyl)-7-methylimidazo[1,2-a]pyridin-3-yl]prop-2-enenitrile (CAS 477847-66-8)
- 3-Bromo-5-methoxy-6-methyl-1H-indazole (CAS 1000343-66-7)
- 8-Chloro-3-ethyl-2,3,4,9-tetrahydro-1h-carbazole (CAS 1498468-96-4)
- 2-chloro-1,3-thiazole-5-sulfonamide (CAS 848362-00-5)
- Gadoxetate Impurity 15 (CAS CATO-C4X-261815)
- Semaglutide Impurity 124 (CAS CATO-C4X-2226124)
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