4-Bromo-5-(difluoromethyl)-1-ethyl-1H-pyrazole CAS 1856046-48-4
| CAS No. | 1856046-48-4 |
| Molecular Formula | C6H7BrF2N2 |
| Molecular Weight | 225.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Bromo-5-(difluoromethyl)-1-ethyl-1H-pyrazole is closely related to a nitrile group, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Bromo-5-(difluoromethyl)-1-ethyl-1H-pyrazole (CAS 1856046-48-4), molecular formula C6H7BrF2N2 and molecular weight 225.03 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-Bromo-5-(difluoromethyl)-1-ethyl-1H-pyrazole (C6H7BrF2N2) contains a nitrile group, fluorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 225.03 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Bromo-5-(difluoromethyl)-1-ethyl-1H-pyrazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H7BrF2N2 |
| Molecular Weight | 225.03 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 4-Bromo-3-(difluoromethyl)-1-ethyl-1H-pyrazole (CAS 1856095-62-9)
- 4-Bromo-1-(2,2-difluoroethyl)-5-methyl-1H-pyrazole (CAS 1946828-50-7)
- 3-Bromo-1-(2,2-difluoroethyl)-4-methyl-1H-pyrazole (CAS 2469102-90-5)
- 4-Bromo-1-(2,2-difluoropropyl)-1H-imidazole (CAS 2167183-58-4)
- 4-Bromo-1-(difluoromethyl)-3,5-dimethyl-1H-pyrazole (CAS 882230-06-0)
- 4-Bromo-5-(2,2-difluoroethyl)-1-methyl-1H-pyrazole (CAS 2306262-80-4)
- 6-Bromo-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde (CAS 1000341-75-2)
- 4-Bromo-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde (CAS 1000341-87-6)
Recommended Standards
- 4-(bromomethyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole (CAS 1694474-39-9)
- 4-(Bromomethyl)-5-(difluoromethyl)-1-methyl-1h-pyrazole (CAS 1525015-38-6)
- N-cyclopropyl-2-iodoacetamide (CAS 1344024-14-1)
- (5R,6R)-3,4-Dichloro-5,6-dihydroxycyclohexa-1,3-dienecarboxylic acid (CAS 205587-32-2)
- 4-Bromo-6-chloro-1H-indazole-3-carbaldehyde (CAS 887568-38-9)
- 1-Bromo-4-(1-methoxycyclobutyl)benzene (CAS 865204-04-2)
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