5,7-Difluoro-4-hydroxyquinoline-3-carboxylic acid CAS 185804-34-6
| CAS No. | 185804-34-6 |
| Molecular Formula | C10H5F2NO3 |
| Molecular Weight | 225.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5,7-Difluoro-4-hydroxyquinoline-3-carboxylic acid (CAS 185804-34-6), molecular formula C10H5F2NO3 and molecular weight 225.15 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5,7-Difluoro-4-hydroxyquinoline-3-carboxylic acid (C10H5F2NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5,7-Difluoro-4-hydroxyquinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H5F2NO3 |
| Molecular Weight | 225.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 6,8-Difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 101830-82-4)
- 7,8-Difluoro-2-oxo-1,2-dihydroquinoline-4-carboxylic acid (CAS 1125702-49-9)
- 6,8-DIfluoro-4-oxo-1,4-dihydroquinoline-2-carboxylic acid (CAS 1267474-18-9)
- 6,7-Difluoro-2-oxo-1,2-dihydroquinoline-4-carboxylic acid (CAS 1269531-40-9)
- 6,7-Difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 144216-11-5)
- 5,7-Difluoro-2-oxo-1,2-dihydroquinoline-3-carboxylic acid (CAS 1592590-69-6)
- 5,7-Difluoro-4-hydroxyquinoline-3-carboxylic acid (CAS 228728-18-5)
- 5,8-Difluoro-4-hydroxyquinoline-3-carboxylic acid (CAS 223690-44-6)
Recommended Standards
- 4-(2-Bromoethoxy)thiane (CAS 1823253-27-5)
- (6-nitrobenzo[1,3]dioxol-5-yl) acetate (CAS 7107-08-6)
- 2-Acetoxy-5-nitrobenzoic acid (CAS 17336-14-0)
- 1-(3,5-Difluorophenyl)-4-nitro-1H-pyrazole (CAS 646037-38-9)
- L-tyrosyl-L-phenylalanyl-L-phenylalanine compound with acetic acid (1:1) (CAS 108322-09-4)
- Torilin (CAS 13018-10-5)
- Ethyl 3-(o-tolyl)propanoate (CAS 104750-61-0)
- 1-(4-Fluoro-1,3-benzothiazol-2-yl)azetidine-3-carboxylic acid (CAS 1283108-55-3)
- 2,7-Dimethylbenzo[lmn][3,8]phenanthroline-2,7-diium tetrafluoroborate (CAS 21178-14-3)
- Methyl 4-fluoro-3-(trifluoromethoxy)benzoate (CAS 1012869-32-7)
- 2-Amino-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 61838-56-0)
- (R)-(2-methylpiperazin-1-yl)(phenyl)methanone (CAS 619331-53-2)
- 2-(5-Ethyl-2,4-dimethyl-6-oxopyrimidin-1(6H)-yl)acetic acid (CAS 1708178-79-3)
- D-[Phe]6-Semaglutide (CAS CATO-CPTD788633)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com