5-Chloro-3-(piperidin-1-ylsulfonyl)pyridin-2-amine CAS 1858250-67-5
| CAS No. | 1858250-67-5 |
| Molecular Formula | C10H14ClN3O2S |
| Molecular Weight | 275.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-Chloro-3-(piperidin-1-ylsulfonyl)pyridin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-Chloro-3-(piperidin-1-ylsulfonyl)pyridin-2-amine (CAS 1858250-67-5) is a high-purity analytical reference standard with the molecular formula C10H14ClN3O2S and a molecular weight of 275.76 g/mol.
Structurally, 5-Chloro-3-(piperidin-1-ylsulfonyl)pyridin-2-amine (C10H14ClN3O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 275.76 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H14ClN3O2S |
| Molecular Weight | 275.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- 3-Chloro-5-(piperidin-1-ylsulfonyl)pyridin-4-amine (CAS 1352515-74-2)
- 1-((2-Chloropyridin-3-yl)sulfonyl)-4-methylpiperazine (CAS 60597-73-1)
- 1-((6-Chloropyridin-3-yl)sulfonyl)-4-methylpiperazine (CAS 64614-53-5)
- 1-(6-chloropyridin-2-yl)-4-methanesulfonylpiperazine (CAS 260441-50-7)
- 6-Methoxybenzo[d]isothiazol-3(2H)-one 1,1-dioxide (CAS 62473-95-4)
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