2-(Bromomethyl)-5-(trifluoromethyl)benzo[b]thiophene CAS 1858256-40-2
| CAS No. | 1858256-40-2 |
| Molecular Formula | C10H6BrF3S |
| Molecular Weight | 295.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 2-(Bromomethyl)-5-(trifluoromethyl)benzo[b]thiophene (CAS 1858256-40-2), a certified reference material (molecular formula C10H6BrF3S, MW 295.12 g/mol) for analytical method development and quality control.
The molecular framework of 2-(Bromomethyl)-5-(trifluoromethyl)benzo[b]thiophene (C10H6BrF3S) is characterized by sulfur-containing functionality, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H6BrF3S |
| Molecular Weight | 295.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Sulfur Atoms | 1 |
Related Bromomethyl Standards
- 2-(Bromomethyl)-7-(trifluoromethyl)benzo[b]thiophene (CAS 1858242-05-3)
- 2-(Bromomethyl)-4-(trifluoromethyl)benzo[b]thiophene (CAS 2377846-69-8)
- 2-(Bromomethyl)-6-(trifluoromethyl)benzo[b]thiophene (CAS 2377846-67-6)
- (Bromomethyl)diphenylphosphine oxide (CAS 119460-28-5)
- 2-(bromomethyl)-4-fluoro-6-(trifluoromethoxy)pyridin-3-amine (CAS 1806185-95-4)
- 6-(Bromomethyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole (CAS 368426-64-6)
- Rel-1-(bromomethyl)-4-((1s,4r)-4-propylcyclohexyl)benzene (CAS 151105-68-9)
- 2-[[3-(bromomethyl)pyrazol-1-yl]methoxy]ethyl-trimethyl-silane (CAS 2283422-16-0)
Recommended Standards
- 2,7-Dichloro-9H-xanthene-9-carboxylic acid (CAS 188027-95-4)
- 4-Iodo-5-methyl-2-phenylpyridine (CAS 1806421-28-2)
- (2-Chlorobenzoyl) 2-chlorobenzoate (CAS 49619-43-4)
- 2-Iodo-5-methyl-4-phenylpyridine (CAS 1803797-19-4)
- 4-(Difluoromethyl)-3-methoxypicolinoyl chloride (CAS 1805121-94-1)
- (S)-1-(amino(phenyl)methyl)naphthalen-2-ol (CAS 219897-38-8)
- 3-(Pyridin-3-yl)propiolic acid hydrochloride (CAS 66954-54-9)
- (4-Phenyl-2-pyrimidinyl)methanamine dihydrochloride (CAS 1211511-88-4)
- 1H-Indole-6-carbaldehyde oxime (CAS 1018038-62-4)
- [(2R,3S,4R,5R)-3,4-diacetoxy-5-(allyloxycarbonylamino)-2-hydroxy-6-oxo-hexyl] acetate (CAS 1374760-23-2)
- 2-(Tert-butyl)-1-ethynylcyclohexan-1-ol (CAS 1393807-33-4)
- 7-Nitroindazole (sodium) (CAS 161467-34-1)
- 4-Aminotetrahydro-2H-thiopyran 1-oxide (CAS 1158698-54-4)
- Hexapeptide-1 (CAS CATO-CPTD788821)
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