N-methyl-4-((4-(trifluoromethyl)pyrimidin-2-yl)oxy)benzenesulfonamide CAS 1858256-57-1
| CAS No. | 1858256-57-1 |
| Molecular Formula | C12H10F3N3O3S |
| Molecular Weight | 333.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-methyl-4-((4-(trifluoromethyl)pyrimidin-2-yl)oxy)benzenesulfonamide (CAS 1858256-57-1), molecular formula C12H10F3N3O3S and molecular weight 333.29 g/mol, is a CATO reference standard with documented purity and traceability.
N-methyl-4-((4-(trifluoromethyl)pyrimidin-2-yl)oxy)benzenesulfonamide (C12H10F3N3O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-methyl-4-((4-(trifluoromethyl)pyrimidin-2-yl)oxy)benzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10F3N3O3S |
| Molecular Weight | 333.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Recommended Standards
- 5-Methoxy-4-[(4-methoxybenzyl)oxy]-2-nitrobenzoic Acid (CAS 1643979-88-7)
- (4E)-2-(2,6-Difluorophenyl)-4-[1-(dimethylamino)-2-(1H-1,2,4-triazol-1-yl)ethylidene]-4,5-dihydro-1,3-oxazol-5-one (CAS 866010-31-3)
- 1,4-Bis(chloromethyl)-2-((2-ethylhexyl)oxy)-5-methoxybenzene (CAS 146370-52-7)
- 2-((1-Methyl-1H-tetrazol-5-yl)thio)-N-(4-(trifluoromethoxy)phenyl)acetamide (CAS 212074-56-1)
- 2,4-Pyrimidinediamine, N2-(4-bromophenyl)-5-fluoro-N4-(phenylmethyl)- (CAS 1956323-18-4)
- 1-(3-methyloxan-3-yl)methanamine (CAS 1158760-03-2)
- 4-(4-Fluoro-3-methylphenyl)-2H-pyrido[2,3-e][1,2,4]thiadiazin-3(4H)-one 1,1-dioxide (CAS 1325305-83-6)
- (5-Cyclopropyltetrahydrofuran-2-yl)methanamine (CAS 1849323-79-0)
- 4-Formyl-2-(trifluoromethyl)benzonitrile (CAS 101066-58-4)
- 2-((3-Cyano-4-(3,4-dimethoxyphenyl)-6-phenylpyridin-2-yl)thio)-N-(2-methoxyphenyl)acetamide (CAS 337499-41-9)
- tert-Butyl (2-((4-aminophenyl)amino)-2-oxoethyl)carbamate (CAS 83209-85-2)
- 2-(Prop-1-yn-1-yl)aniline (CAS 220465-91-8)
- 2-(6-Cyano-5-(difluoromethyl)-4-nitropyridin-2-yl)acetic acid (CAS 1804423-79-7)
- D-Ala28-Tirzepatide (CAS CATO-CPTD788906)
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