6-Phenyl-[1,2,4]triazolo[4,3-b]pyridazin-8-ol CAS 18591-71-4
| CAS No. | 18591-71-4 |
| Molecular Formula | C18H20ClNO |
| Molecular Weight | 301.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
6-Phenyl-[1,2,4]triazolo[4,3-b]pyridazin-8-ol (CAS 18591-71-4) is a high-purity analytical reference standard with the molecular formula C18H20ClNO and a molecular weight of 301.81 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 6-Phenyl-[1,2,4]triazolo[4,3-b]pyridazin-8-ol is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 301.81 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 6-Phenyl-[1,2,4]triazolo[4,3-b]pyridazin-8-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H20ClNO |
| Molecular Weight | 301.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Phenyl Standards
- 4-(4-([1,2,4]Triazolo[4,3-a]pyridin-3-yl)piperidin-1-yl)-4-oxobutanoic acid (CAS 1189749-41-4)
- 5-Methyl-[1,2,4]triazolo[4,3-a]pyridine (CAS 5528-51-8)
- N-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-2,5-dimethylbenzenesulfonamide (CAS 1112017-68-1)
- 2-([1,2,4]Triazolo[4,3-a]pyridin-3-ylthio)-N-(2-cyano-3-methylbutan-2-yl)acetamide (CAS 757203-22-8)
- 4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5-(6-methyl-pyridin-2-yl)-1H-imidazole-2-carbaldehyde (CAS 1352609-91-6)
- 6-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl 4-methylbenzenesulfonate (CAS 478046-23-0)
- 4-{6-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-5-yl}-2-phenyl-1,3-thiazole (CAS 478067-25-3)
- 5-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-4-methyl-1-(m-tolyl)-1H-imidazol-2(3H)-one (CAS 1043908-08-2)
Recommended Standards
- 3-[2-Chloro-4-(1-methyl-1-phenylethyl)phenoxy]azetidine (CAS 1219960-83-4)
- (2-Amino-5-chlorophenyl)(cyclopentyl)(phenyl)methanol (CAS 893766-57-9)
- (6-Chloropyridin-3-yl)(4-hexylphenyl)methanone (CAS 1187169-45-4)
- (4-Chlorophenyl)(cyclohexyl)(pyridin-4-yl)methanol (CAS 439929-28-9)
- Timolol D9 Maleate (CAS CATO-C4X-149630)
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- 7-Fluoro-2-mercaptoquinazolin-4(3H)-one (CAS 69661-43-4)
- 6-isothiocyanatohex-1-ene (CAS 49776-81-0)
- (3S,5S)-5-(3-(Cyclopentyloxy)-4-methoxyphenyl)-3-(3-methylbenzyl)piperidin-2-one (CAS 617720-02-2)
- PIPERIDINE-3-CARBOXAMIDE HCL (CAS 1019852-04-0)
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