6-Methyl-[1,2,4]triazolo[4,3-b]pyridazine CAS 18591-78-1

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Methyl-[1,2,4]triazolo[4,3-b]pyridazine.

6-Methyl-[1,2,4]triazolo[4,3-b]pyridazine (CAS 18591-78-1), molecular formula C6H6N4 and molecular weight 134.14 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 6-Methyl-[1,2,4]triazolo[4,3-b]pyridazine (C6H6N4) contains a nitrile group, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 134.14 g/mol, it falls into the low-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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