benzyl trans-3-azido-4-fluoro-pyrrolidine-1-carboxylate CAS 186201-06-9
| CAS No. | 186201-06-9 |
| Molecular Formula | C12H13FN4O2 |
| Molecular Weight | 264.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
benzyl trans-3-azido-4-fluoro-pyrrolidine-1-carboxylate (CAS 186201-06-9), molecular formula C12H13FN4O2 and molecular weight 264.26 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, benzyl trans-3-azido-4-fluoro-pyrrolidine-1-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 264.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H13FN4O2 |
| Molecular Weight | 264.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Recommended Standards
- benzyl cis-3-azido-4-fluoro-pyrrolidine-1-carboxylate (CAS 185692-25-5)
- 3-Nitro-2-(phenylsulfonyl)pyridine (CAS 188429-02-9)
- 5-Methyl-7-(methylsulfonyl)-4-oxo-3,4-dihydropyrido[4,3-d]pyrimidine-8-carbonitrile (CAS 1604041-59-9)
- (2R-3R-4S-5R-6S)-3-4-5-Trihydroxy-2-hydroxymethyl-7-9-diaza-1-oxa-spiro[4-5]decane-10-one-8-thione (CAS 189633-62-3)
- GHRP-3·TFA salt (CAS 259230-56-3(Free Base))
- N-(2-(ethylamino)ethyl)-4-methylthiazole-5-carboxamide hydrochloride (CAS 1829939-35-6)
- ((2S,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate (CAS 66004-77-1)
- N,5-Dimethyloxazole-4-carboxamide (CAS 1003044-01-6)
- 8-Amino-1-naphthol-3,6-disulfonic acid monosodium salt monohydrate (CAS 312693-54-2)
- DiiSopropyl (2-aminophenyl)phosphonate (CAS 1073561-75-7)
- tert-Butyl (4-bromocyclohexyl)carbamate (CAS 1353963-71-9)
- 3-Chloro-1h-pyrazolo[3,4-b]pyrazine (CAS 1260773-79-2)
- 1-[3-(3-Fluorophenyl)-1,2,4-thiadiazol-5-yl]piperazine (CAS 1417825-51-4)
- 263251-78-1 NMG938VJ6T D-3 Tavilermide [USAN:INN] UNII-NMG938VJ6T MIM-D3 MIM-D 3 D 3 (peptide) Tavilermide (CAS 263251-78-1)
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