Ticagrelor Impurity 75 (Mixture of Diastereomers) CAS 1863036-45-6
| CAS No. | 1863036-45-6 |
| Molecular Formula | C17H24ClN5O5S |
| Molecular Weight | 445.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Ticagrelor Impurity 75 (Mixture of Diastereomers) (CAS 1863036-45-6, C17H24ClN5O5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, Ticagrelor Impurity 75 (Mixture of Diastereomers) is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 445.92 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ticagrelor Impurity 75 (Mixture of Diastereomers) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H24ClN5O5S |
| Molecular Weight | 445.92 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor Impurity 127 (CAS CATO-C4X-1093127)
- Ticagrelor Impurity 18 (CAS CATO-C4X-109318)
- Ticagrelor Impurity 112 (CAS CATO-C4X-1093112)
- Ticagrelor Impurity 35 (CAS CATO-C4X-109335)
- Ticagrelor Impurity 48 (CAS CATO-C4X-109348)
- Ticagrelor Impurity 119 (CAS CATO-C4X-1093119)
- Ticagrelor Impurity 76 (Mixture of Diastereomers) (CAS CATO-C4X-109376)
- Ticagrelor Impurity 116 (CAS 1863036-47-8)
Recommended Standards
- Edoxaban Impurity 69 (CAS CATO-C4X-106369)
- 2-(3-Bromophenyl)-5-(dibromomethyl)benzo[d]oxazole (CAS 1706430-05-8)
- N-(7-((4-Chlorophenyl)(hydroxy)methyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-4-methylbenzenesulfonamide (CAS 886493-40-9)
- (E)-[1-(4-Chlorophenyl)-3-(4-methylbenzenesulfonyl)propylidene][(3-fluorophenyl)methoxy]amine (CAS 477867-78-0)
- Azasetron Impurity 1 (CAS 123040-79-9)
- Sodium Cromoglicate Impurity 10 (CAS 50521-64-7)
- Ilaprazole Impurity 57 Iodized Salt (CAS 1508282-92-5)
- 3-Cyano-4,6-dimethylpyridin-2-yl 2-chloro-4-(methylsulfonyl)benzoate (CAS 338421-40-2)
- 2-(4-Bromophenoxy)-1-(4-((4-fluorophenyl)sulfonyl)piperazin-1-yl)ethanone (CAS 439939-70-5)
- Methyl 1-amino-3-fluorocyclobutane-1-carboxylate (CAS 1782412-49-0)
- 4-(Morpholine-4-carbonyl)benzene-1-sulfonyl chloride (CAS 881005-36-3)
- 4-Ethynyl-2,5-dimethoxybenzaldehyde (CAS 1208264-50-9)
- 5-methyl-1-phenylhexan-1-one (CAS 25552-17-4)
- Tirzepatide Impurity 44 (CAS CATO-C4X-324044)
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