4-[(4-Chloro-2-fluorophenyl)methyl]morpholine CAS 1866791-31-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1866791-31-2
Molecular FormulaC11H13ClFNO
Molecular Weight229.68 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-[(4-Chloro-2-fluorophenyl)methyl]morpholine CAS 1866791-31-2 chemical structure

Description

The occurrence of 4-[(4-Chloro-2-fluorophenyl)methyl]morpholine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-[(4-Chloro-2-fluorophenyl)methyl]morpholine (CAS 1866791-31-2), molecular formula C11H13ClFNO and molecular weight 229.68 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 4-[(4-Chloro-2-fluorophenyl)methyl]morpholine is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 229.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-[(4-Chloro-2-fluorophenyl)methyl]morpholine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H13ClFNO
Molecular Weight229.68 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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