2-(3-Chloro-4-fluorophenyl)-1H-indole CAS 1868-88-8
| CAS No. | 1868-88-8 |
| Molecular Formula | C14H9ClFN |
| Molecular Weight | 245.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-(3-Chloro-4-fluorophenyl)-1H-indole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
2-(3-Chloro-4-fluorophenyl)-1H-indole (CAS 1868-88-8), molecular formula C14H9ClFN and molecular weight 245.68 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(3-Chloro-4-fluorophenyl)-1H-indole (C14H9ClFN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H9ClFN |
| Molecular Weight | 245.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 5-Chloro-2-fluoro-N-(3-methoxypropyl)benzamide (CAS 1090033-19-4)
- N-(2-chloro-6-fluorobenzyl)-N-ethylglycine (CAS 1181702-16-8)
- 2-chloro-N-[2-(2-fluorophenoxy)ethyl]-N-methylacetamide (CAS 1182438-10-3)
- Ethyl (2-chloro-6-fluorobenzyl)glycinate (CAS 1184214-65-0)
- Methyl (2-chloro-6-fluorobenzyl)alaninate (CAS 1222685-46-2)
- 2-Chloro-n-[3-(2-fluorophenoxy)propyl]acetamide (CAS 1226215-91-3)
- 2-Chloro-4-(3-fluoro-4-methylphenyl)benzonitrile (CAS 1355247-63-0)
- 4-(2-Chloro-5-methylphenyl)-2-fluorobenzonitrile (CAS 1381944-54-2)
Recommended Standards
- 4-Cyano-3-(hydroxymethyl)-2-methylbenzene-1-sulfonyl chloride (CAS 1807239-47-9)
- 1-Formylindoline-5-sulfonyl chloride (CAS 79679-16-6)
- 4-Cyano-3-ethyl-2-hydroxybenzene-1-sulfonyl chloride (CAS 1805653-86-4)
- 1-Oxo-1,2,3,4-tetrahydroisoquinoline-7-sulfonyl Chloride (CAS 952424-09-8)
- (R)-Methyl 2-(((benzyloxy)carbonyl)amino)-3-phenylpropanoate (CAS 37440-07-6)
- 2-Fluoro-1,3-dimethylimidazolidin-1-ium hexafluorophosphate(V) (CAS 164298-27-5)
- Ethyl 4-bromo-2-fluoro-5-hydroxybenzoate (CAS 1694637-07-4)
- 1-(3-Chlorophenyl)cyclohexan-1-amine (CAS 959140-90-0)
- [3-(1,3-Oxazol-2-yl)phenyl]methanamine;hydrochloride (CAS 1799421-14-9)
- 4-Ethynyl-4'-fluoro-1,1'-biphenyl (CAS 58609-43-1)
- 6,7-dimethyl-1,5-dihydropyrrolo[3,2-d]pyrimidine-2,4-dione (CAS 1062517-27-4)
- 3-(4-iodophenyl)-6-methyl-1,2,4,5-tetrazine (CAS 56108-04-4)
- (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-(3-hydroxybenzyl)propanoic acid (CAS 1260615-23-3)
- Protein Kinase C (19-36) Peptide (CAS 113731-96-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com