Fosfomycin Impurity 18 CAS 18689-36-6

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.18689-36-6
Molecular FormulaC7H15O3P
Molecular Weight178.17 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Fosfomycin Impurity 18 CAS 18689-36-6 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Fosfomycin Impurity 18.

As a process- or degradation-related impurity, Fosfomycin Impurity 18 (CAS 18689-36-6, C7H15O3P) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Fosfomycin Impurity 18 (C7H15O3P) contains a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H15O3P
Molecular Weight178.17 g/mol
Purity>95%
StorageStore at 2-8°C, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityHygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)0.5
CAS Registry Year (est.)1962

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