5-chloro-3-[3,5-di(trifluoromethyl)phenyl]-1,2,4-thiadiazole CAS 186982-51-4
| CAS No. | 186982-51-4 |
| Molecular Formula | C10H3ClF6N2S |
| Molecular Weight | 332.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution, 5-chloro-3-[3,5-di(trifluoromethyl)phenyl]-1,2,4-thiadiazole is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 332.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
5-chloro-3-[3,5-di(trifluoromethyl)phenyl]-1,2,4-thiadiazole (CAS 186982-51-4), molecular formula C10H3ClF6N2S and molecular weight 332.65 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H3ClF6N2S |
| Molecular Weight | 332.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related chloro Standards
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2,2-difluoro-N-(2-methoxyethyl)acetamide (CAS 1823184-09-3)
- Methyl 4-chloro-6-oxo-1-(3-(trifluoromethyl)phenyl)-1,6-dihydropyridazine-3-carboxylate (CAS 129109-18-8)
- 1823184-19-5 3-chloro-6'-methoxy-5-(trifluoromethyl)-[2,3'-bipyridine]-5'-carboxylic acid KS-000025PS (CAS 1823184-19-5)
- 3-Chloro-2-{5-[(1Z)-2-nitroprop-1-en-1-yl]-1H-pyrazol-1-yl}-5-(trifluoromethyl)pyridine (CAS 318248-57-6)
- 3-Chloro-N'-{[5-oxo-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}benzohydrazide (CAS 338975-57-8)
- 4-Chloro-N'-{[5-oxo-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}benzohydrazide (CAS 338975-58-9)
- 1-(4-(2-Chloro-6-fluoro-4-(trifluoromethyl)phenoxy)phenyl)ethan-1-one (CAS 914637-09-5)
- 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-fluorophenyl)acetamide (CAS 672950-14-0)
Recommended Standards
- 3-Nitro-4-(trifluoroacetamido)benzene-1-sulfonyl chloride (CAS 1178647-96-5)
- N,N-Diethyl-2-((3-(trichloromethyl)-1,2,4-thiadiazol-5-yl)oxy)acetamide (CAS 89781-21-5)
- 1-(2-(4-Bromo-2-chlorophenoxy)ethyl)-4-methylpiperidine (CAS 401801-85-2)
- [3-(4-{[(tert-butyldimethylsilyl)oxy]methyl}phenyl)prop-1-yn-1-yl]trimethylsilane (CAS 1803601-80-0)
- 4-[(4-Fluorophenyl)sulfonyl]piperidine hydrochloride (CAS 150221-22-0)
- Tert-butyl 3-(3-hydroxybutan-2-yl)azetidine-1-carboxylate (CAS 2231675-36-6)
- 5-(1-Aminobutyl)-2-methoxyphenol (CAS 1270404-63-1)
- 3-Fluoro-4-(3-(piperazin-1-yl)propoxy)phenylboronic acid (CAS 1704064-06-1)
- N-(3-ethynylphenyl)cyclohexanecarboxamide (CAS 949761-85-7)
- Atorvastatin Impurity 67 (CAS 693793-87-2)
- Methyl 4-(2-((1-methoxypropan-2-yl)amino)-2-oxoacetamido)benzoate (CAS 920402-50-2)
- 3-((2-((2-Chloroethyl)amino)ethyl)amino)propyl dihydrogen phosphate (CAS 45164-26-9)
- [cis-4-fluoro-1-[(1-methyl-1H-pyrazol-4-yl)methyl]pyrrolidin-2-yl]methanamine (CAS 1820575-42-5)
- Human glucagon CRS (CAS 9007-92-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com