2-(6-Hydroxynaphthalen-1-yl)acetic acid CAS 18705-35-6
| CAS No. | 18705-35-6 |
| Molecular Formula | C12H10O3 |
| Molecular Weight | 202.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(6-Hydroxynaphthalen-1-yl)acetic acid.
CATO supplies 2-(6-Hydroxynaphthalen-1-yl)acetic acid (CAS 18705-35-6), a certified reference material (molecular formula C12H10O3, MW 202.21 g/mol) for analytical method development and quality control.
The molecular framework of 2-(6-Hydroxynaphthalen-1-yl)acetic acid (C12H10O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(6-Hydroxynaphthalen-1-yl)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10O3 |
| Molecular Weight | 202.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
Related Hydroxynaphthalen Standards
- 2-(2-Hydroxynaphthalen-1-yl)acetic acid (CAS 10441-45-9)
- 2-(1-Hydroxynaphthalen-2-yl)acetic acid (CAS 10441-47-1)
- 7-Hydroxynaphthalen-2-yl acetate (CAS 146744-23-2)
- 2-(5-Hydroxynaphthalen-1-yl)acetic acid (CAS 3812-96-2)
- 5-hydroxynaphthalen-1-yl acetate 94807-85-9 (CAS 94807-85-9)
- N-(6-hydroxynaphthalen-1-yl)acetamide (CAS 5400-20-4)
- 1-(2-hydroxynaphthalen-1-yl)propan-1-one (CAS 33828-93-2)
- 1-(6-Hydroxynaphthalen-2-yl)propan-1-one (CAS 33828-92-1)
Recommended Standards
- 5-Phenoxypyrimidine-2,4-diamine (CAS 18593-41-4)
- Methyl 5-aminoisoquinoline-6-carboxylate (CAS 187732-93-0)
- Ethyl quinazoline-8-carboxylate (CAS 1823945-25-0)
- Methyl 4-(pyridin-3-yl)-1H-pyrrole-3-carboxylate (CAS 188524-69-8)
- rel-N-[(1R,4R)-4-(Hydroxymethyl)-2-cyclopenten-1-yl]carbamic Acid 1,1-Dimethylethyl Ester (CAS 172720-97-7)
- 2-(3-methoxyphenyl)azetidine (CAS 777887-12-4)
- 2-(1H-benzo[d]imidazol-1-yl)butanoic acid (CAS 876708-69-9)
- (3,5-Dimethylphenyl)(quinolin-3-yl)methanone (CAS 1187169-98-7)
- Ethyl 2-Amino-4-methyl-5-[(piperidin-1-yl)carbonyl]thiophene-3-carboxylate (CAS 297182-53-7)
- (2-(Piperidin-1-ylmethyl)phenyl)(m-tolyl)methanone (CAS 898751-68-3)
- (7-Bromoquinolin-3-yl)methanol (CAS 1956331-52-4)
- 3-{[(2,6-dichlorophenyl)methyl]sulfanyl}-5H,6H-benzo[h]cinnoline (CAS 383148-30-9)
- Ethyl 3-(3-bromophenyl)-2-hydroxypropanoate (CAS 1537329-13-7)
- Compstatin control peptide (CAS 301544-78-5)
Why CATO?
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