3-Ethynyl-1-(2,2,2-trifluoroethyl)pyrrolidin-3-ol CAS 1871896-47-7
| CAS No. | 1871896-47-7 |
| Molecular Formula | C8H10F3NO |
| Molecular Weight | 193.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Ethynyl-1-(2,2,2-trifluoroethyl)pyrrolidin-3-ol (CAS 1871896-47-7), molecular formula C8H10F3NO and molecular weight 193.17 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 3-Ethynyl-1-(2,2,2-trifluoroethyl)pyrrolidin-3-ol is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 193.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Ethynyl-1-(2,2,2-trifluoroethyl)pyrrolidin-3-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10F3NO |
| Molecular Weight | 193.17 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethynyl Standards
- 3'-Ethynyl-[1,1'-biphenyl]-3-amine (CAS 1379319-73-9)
- 4'-Ethynyl-[1,1'-biphenyl]-2-amine (CAS 723748-82-1)
- 4'-Ethynyl-[1,1'-biphenyl]-4-amine (CAS 874362-76-2)
- 4-Ethynyl-1-methyldecahydroquinolin-4-ol (CAS 54924-02-6)
- 4-Ethynyl-2-methyl-decahydro-quinolin-4-ol 59693-01-5 6408AE C12H19NO (CAS 59693-01-5)
- 2-Ethynyl-5-hexylthiophene (CAS 710338-92-4)
- 2-ethynyl-6-methoxynaphthalene (CAS 129113-00-4)
- 2-Ethynyl-2'-methyl-1,1'-biphenyl (CAS 1449574-70-2)
Recommended Standards
- N-methyl-3-(trifluoromethyl)bicyclo[1.1.1]Pentane-1-carboxamide (CAS 1864524-41-3)
- N-(3-(trifluoromethyl)bicyclo[1.1.1]Pentan-1-yl)acetamide (CAS 1886966-97-7)
- 3-(1,3-Dioxolan-2-yl)-4-fluorobenzonitrile (CAS 1823921-62-5)
- N-(bicyclo[1.1.1]Pentan-1-ylmethyl)-2,2,2-trifluoroacetamide (CAS 1886967-44-7)
- cis-3-Hexenyl Butyrate (CAS 16491-36-4)
- 2-Hydroxy-4-methoxy-5-nitrobenzoic acid (CAS 723284-11-5)
- 4,5-Dichloro-2-methylquinoline (CAS 63010-74-2)
- Methyl 2-(4-((methylamino)methyl)phenoxy)acetate (CAS 940365-01-5)
- 3,4-Difluoro-L-phenylalanine (CAS 31105-90-5)
- 2-Chloro-5-((4-(trifluoromethyl)pyrimidin-2-yl)amino)benzoic acid (CAS 1456213-79-8)
- Tiaramide hydrochloride (CAS 35941-71-0)
- 1-(4-Methoxypyridin-2-yl)-N-methylmethanamine dihydrochloride (CAS 1559059-77-6)
- 5-(2-Chloropyrimidin-4-yl)-2-methoxybenzonitrile (CAS 1292317-51-1)
- Semaglutide Impurity 147 (CAS CATO-C4X-2226147)
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