6-Bromo-8-methyl-3,4-dihydroquinolin-2(1H)-one CAS 1872-69-1
| CAS No. | 1872-69-1 |
| Molecular Formula | C10H10BrNO |
| Molecular Weight | 240.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Bromo-8-methyl-3,4-dihydroquinolin-2(1H)-one.
6-Bromo-8-methyl-3,4-dihydroquinolin-2(1H)-one (CAS 1872-69-1) is a high-purity analytical reference standard with the molecular formula C10H10BrNO and a molecular weight of 240.10 g/mol.
The molecular framework of 6-Bromo-8-methyl-3,4-dihydroquinolin-2(1H)-one (C10H10BrNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Bromo-8-methyl-3,4-dihydroquinolin-2(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10BrNO |
| Molecular Weight | 240.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 7-Bromo-1-isopropyl-1H-imidazo[4,5-c]pyridine (CAS 1044771-43-8)
- 7-Bromo-1-ethyl-2-methyl-1h-imidazo[4,5-c]pyridine (CAS 1044771-90-5)
- 4-Bromo-6-methoxy-7-methyl-1H-indole (CAS 1082040-81-0)
- 1-bromo-4-(2-isocyanatopropyl)benzene (CAS 1082787-37-8)
- 7-Bromo-1-methyl-3,4-dihydroquinolin-2(1H)-one (CAS 1086386-20-0)
- 6-Bromo-1-methyl-1,2,3,4-tetrahydroquinolin-2-one (CAS 1092523-03-9)
- 5-Bromo-2-methyl-3,4-dihydroisoquinolin-1(2H)-one (CAS 1100509-38-3)
- 3-Bromo-5-(1-methylethoxy)-benzonitrile (CAS 1119779-02-0)
Recommended Standards
- Aziridin-1-yl(4-bromo-3-methylphenyl)methanone (CAS 1864123-47-6)
- 8-Bromo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-1-one (CAS 187833-72-3)
- 3-Bromo-6-methyl-2,3-dihydroquinolin-4(1H)-one (CAS 1824060-43-6)
- Ethyl hexafluoroisopropyl carbonate (CAS 18925-64-9)
- 2-Methoxy-N-((5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)methyl)ethan-1-amine (CAS 919347-14-1)
- 17AVG63ZBC 7791-13-1 Cobaltous chloride hexahydrate Cobalt chloride, hexahydrate Cobalt(II) chloride, hexahydrate Cobalt chloride (CoCl2), hexahydrate CCRIS 7729 Chlorek cobaltawy [Polish] Cobalt chloride hexahydrate Cobalt dichloride hexahydrate Cobalt(II) chloride hexahydrate Cobaltous chloride, hexahydrate Chlorek cobaltawy UNII-17AVG63ZBC (CAS 7791-13-1)
- n-Benzyl-2-(5-bromo-2-ethoxy-4-formylphenoxy)acetamide (CAS 832674-54-1)
- 3-Bromo-5-(methoxymethyl)isoxazole (CAS 1220521-36-7)
- 2-(2,3-Difluorophenyl)[1,3]dioxolane (CAS 773101-60-3)
- 2-Fluoromethyl-piperazine-1,4-dicarboxylic acid di-tert-butyl ester (CAS 2331260-27-4)
- 2-Chloro-3-hydroxybenzaldehyde (CAS 56962-10-8)
- (E)-octadec-9-enoic anhydride (CAS 55726-25-5)
- 1-(Tert-butoxy)-4-methylbenzene (CAS 15359-98-5)
- 3X Flag Peptide trifluoroacetate salt (CAS 402750-12-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com