1-(3-(Chloromethyl)azetidin-1-yl)ethan-1-one CAS 1872005-46-3
| CAS No. | 1872005-46-3 |
| Molecular Formula | C6H10ClNO |
| Molecular Weight | 147.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(3-(Chloromethyl)azetidin-1-yl)ethan-1-one (CAS 1872005-46-3), molecular formula C6H10ClNO and molecular weight 147.60 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(3-(Chloromethyl)azetidin-1-yl)ethan-1-one (C6H10ClNO) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 1-(3-(Chloromethyl)azetidin-1-yl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H10ClNO |
| Molecular Weight | 147.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloromethyl Standards
- 5-(Chloromethyl)-3-ethyl-4,5-dihydro-1,2-oxazole (CAS 1311317-47-1)
- 6-(chloromethyl)piperidin-2-one (CAS 1315366-70-1)
- 1-(Chloromethyl)piperidin-2-one (CAS 68116-79-0)
- 2-(Chloromethyl)-4,4-dimethyl-4,5-dihydrooxazole (CAS 74307-97-4)
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Recommended Standards
- 5-Chloroazepan-2-one (CAS 1468-56-0)
- Piperidine-4-carbonyl chloride (CAS 190142-48-4)
- 1-Piperidine acid chloride (CAS 13939-69-0)
- (E)-4-Chloro-N,N-dimethylbut-2-enamide (CAS 51830-58-1)
- N-(5-Bromo-4-methyl-2-pyridinyl)-N-(3-ethoxypropyl)amine (CAS 1220036-71-4)
- 4-Isopropyl-2-oxopyrrolidine-3-carboxylic acid (CAS 90088-26-9)
- 5-Bromo-N-(6-methoxypyridin-3-yl)nicotinamide (CAS 524924-30-9)
- 1-(2-Ethyl-3-hydroxy-2-methylpropyl)pyrrolidin-3-ol (CAS 1344288-73-8)
- 4-(1,3,4-Oxadiazol-2-yl)piperidine hydrochloride (CAS 1384079-20-2)
- N-(4-Fluorophenyl)-6-nitroquinazolin-4-amine (CAS 691385-33-8)
- Dysprosium(III) sulfate octahydrate (CAS 10031-50-2)
- 2-(Methylsulfanyl)-4-(2,4,5-trichlorophenoxy)-6-(trifluoromethyl)pyrimidine (CAS 477845-99-1)
- 1-(2,3-Dihydro-4H-benzo[b][1,4]thiazin-4-yl)ethan-1-one (CAS 6397-16-6)
- 81988-89-8 UH11FDQ454 Ramoplanin A(sub 3) Ramoplanin A3 (S)-2-(3-Chloro-4-hydroxyphenyl)-N-(N(sup 2)-((2Z,4Z)-8-methyl-2,4-nonadienoyl)-(S)-asparaginyl-(2S,3S)-3-hydroxyasparaginyl-(R)-2-(p-hydroxyphenyl)glycyl-(R)-ornithyl-(2R,3R)-allothreonyl-2-(p-hydroxyphenyl)glycyl-2-(p-hydroxyphenyl)glycyl-(2S,3S)-allothreonyl-(S)-phenylalanyl-(R)-ornithyl-(S)-2-(p-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycyl-(2R,3R)-allothreonyl-(S)-2-(p-hydroxyphenyl)glycylglycyl-(S)-leucyl-(R)-alanyl)glycine psi1-lactone Ramoplanin A 1 (peptide moiety), 1-(N(sup 2)-methyl-1-oxo-2,4-nonadienyl)-L-asparagine)-11-(L-2-(4-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycine)-, (Z,Z)- UNII-UH11FDQ454 (CAS 81988-89-8)
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