(S)-6-((2,4-Difluorobenzyl)oxy)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine CAS 187235-32-1
| CAS No. | 187235-32-1 |
| Molecular Formula | C13H11F2N3O4 |
| Molecular Weight | 311.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (S)-6-((2,4-Difluorobenzyl)oxy)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (S)-6-((2,4-Difluorobenzyl)oxy)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (CAS 187235-32-1), a certified reference material (molecular formula C13H11F2N3O4, MW 311.24 g/mol) for analytical method development and quality control.
The molecular framework of (S)-6-((2,4-Difluorobenzyl)oxy)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (C13H11F2N3O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H11F2N3O4 |
| Molecular Weight | 311.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related S Standards
- 1-Boc-4-(2,4-difluorobenzyl)piperazine (CAS 1065586-31-3)
- N-(2,4-Difluorobenzyl)-2-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetamide (CAS 1170077-43-6)
- 3-(1-(3,5-Difluorobenzyl)-1H-indol-3-yl)acrylic acid (CAS 307352-81-4)
- 2-(2,4-Difluorobenzyl)-5-methyl-2H-1,2,6-thiadiazine-4-carboxylic acid 1,1-dioxide (CAS 1775552-19-6)
- N-(2,6-Difluorobenzyl)-3-(pyrazin-2-yl)-1,2,4-oxadiazole-5-carboxamide (CAS 1235192-31-0)
- 8-((2,6-Difluorobenzyl)oxy)-2-methylimidazo[1,2-a]pyridine-3-carboxylic acid (CAS 1415501-19-7)
- N-(2,5-difluorobenzyl)-6-methyl-4-oxo-4,5-dihydro-[1,2,3]triazolo[1,5-a]pyrazine-3-carboxamide (CAS 1396861-40-7)
- 1-(2,3-Difluorobenzyl)-4-iodo-1H-pyrazole (CAS 1478042-30-6)
Recommended Standards
- 5-((Bis(carboxymethyl)amino)methyl)isophthalic acid (CAS 1446419-86-8)
- 1-(4-Bromophenyl)-4,4,6-trimethyl-1,4-dihydropyrimidine-2-thiol (CAS 37489-47-7)
- 4-(3-bromophenyl)-N-(2-methylpropyl)-1,3-thiazol-2-amine (CAS 1275853-51-4)
- 2-Acetoxy-4-nitro-benzaldiacetate (CAS 54362-25-3)
- methyl 3-aminooxetane-3-carboxylate (CAS 1363383-31-6)
- 2-(4-Bromo-3-methyl-1h-pyrazol-1-yl)-2-methylpropanoic acid (CAS 1006473-56-8)
- 4-(Azetidin-3-ylmethyl)morpholine Dihydrochloride (CAS 1323155-31-2)
- 2-(Naphthalen-2-yl)pyridine (CAS 66318-88-5)
- 59935-32-9 L-Serine-15N MFCD00144672 (CAS 59935-32-9)
- 4-Amino-5-(quinolin-2-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 896837-03-9)
- 1-(Carbamoylmethyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 1410089-07-4)
- Carminomicin I (CAS 50935-04-1)
- Tert-butyl (S)-2-butylpiperazine-1-carboxylate hydrochloride (CAS 1217482-46-6)
- D-[Thr]7-Liraglutide (CAS CATO-C4X-199237)
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