8-((4-Nitrophenyl)thio)quinoline CAS 1873-66-1
| CAS No. | 1873-66-1 |
| Molecular Formula | C15H10N2O2S |
| Molecular Weight | 282.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 8-((4-Nitrophenyl)thio)quinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
8-((4-Nitrophenyl)thio)quinoline (CAS 1873-66-1) is a high-purity analytical reference standard with the molecular formula C15H10N2O2S and a molecular weight of 282.32 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, 8-((4-Nitrophenyl)thio)quinoline is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 282.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C15H10N2O2S |
| Molecular Weight | 282.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Nitrophenyl Standards
- 2-(4-Nitrophenyl)-4-phenylthiazole (CAS 1093215-83-8)
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Recommended Standards
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- Phenylsilanetriyl triacetate (CAS 18042-54-1)
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- 1H-1,2,4-Triazol-5(4H)-one (CAS 122333-30-6)
- n,n-Dimethyl-3-phenylisoxazole-5-carboxamide (CAS 169272-00-8)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(2,6-dichlorophenyl)acetonitrile (CAS 338407-06-0)
- 1-Chloro-3-(2-fluorophenyl)propan-2-one (CAS 144340-73-8)
- Sodium 2-methylpropane-1-sulfinate (CAS 39170-40-6)
- Phenylmagnesium Iodide (ca. 42% in Ethyl Ether, ca. 2mol/L) (CAS 16002-63-4)
- 2-(Bromomethyl)-5-(difluoromethyl)-3-fluoropyridine-4-acetonitrile (CAS 1804372-69-7)
- 2-(Chloromethyl)-3,5-diamino-4-(difluoromethyl)pyridine (CAS 1804986-57-9)
- Des-Pro36-37-Tirzepatide (CAS CATO-CPTD788938)
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