Dabigatran impurity 140 CAS 1873316-01-8
| CAS No. | 1873316-01-8 |
| Molecular Formula | C34H41N7O5 |
| Molecular Weight | 627.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Dabigatran impurity 140 (CAS 1873316-01-8), a pharmacopoeial impurity reference standard (molecular formula C34H41N7O5, MW 627.73 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Dabigatran impurity 140 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 627.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Dabigatran impurity 140 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C34H41N7O5 |
| Molecular Weight | 627.73 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 7 |
Related Dabigatran Standards
- DABIGATRAN ETEXILATE (CAS 1610666-09-5)
- Dabigatran Impurity 11 (CAS 1610758-20-7)
- Dabigatran Impurity 125 (CAS 2225986-94-5)
- Dabigatran Impurity 2 (CAS 2225986-95-6)
- Dabigatran Impurity 3 (CAS 1610758-22-9)
- Dabigatran Impurity 33 (CAS CATO-C4X-108933)
- Dabigatran Impurity 92 (CAS 211915-06-9)
- Dabigatran Etexilate USP Related Compound A (CAS 1408238-40-3)
Recommended Standards
- 8’-Hydroxy-dihydroergocristineDISCONTINUED (CAS 883718-08-9)
- (S)-3-((S)-2-(4,4-Dimethyl-2,5-dioxo-3-(4-(3-(o-tolyl)ureido)benzyl)imidazolidin-1-yl)-4-methylpentanamido)-3-phenylpropanoic acid (CAS 479203-71-9)
- Angiotensin I/II (3-7) (CAS 122483-84-5)
- MeOSuc-Ala-Ala-Pro-Val-AMC (CAS 72252-90-5)
- N-Nitroso Amoxicillin Impurity 104 (CAS CATO-C4X-1148104)
- Triamcinolone Acetonide Impurity 39 (CAS 85197-66-6)
- Rosuvastatin Impurity 125 (CAS CATO-C4X-1169125)
- Baloxavir Marboxil Impurity 190 (CAS CATO-C4X-2108190)
- 2-Cyanomethyl-morpholine-4-carboxylic acid tert-butyl ester (CAS 259180-69-3)
- 1H-Pyrazole-3-carboxylic acid, 4-ethyl-, hydrochloride (1:1) (CAS 2445794-88-5)
- 1-Bromo-2-methylheptane (CAS 72279-59-5)
- 5-(1-Ethyl-1h-pyrazol-4-yl)-1,3,4-oxadiazole-2-thiol (CAS 1004643-47-3)
- (R)-3-Amino-4,4,4-trifluorobutan-1-ol (CAS 881539-56-6)
- Semaglutide (CAS CATO-C4X-2226105)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com