Tert-butyl (S)-3,3-difluoro-4-hydroxypyrrolidine-1-carboxylate CAS 1873374-41-4
| CAS No. | 1873374-41-4 |
| Molecular Formula | C9H15F2NO3 |
| Molecular Weight | 223.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 223.22 g/mol gives Tert-butyl (S)-3,3-difluoro-4-hydroxypyrrolidine-1-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Tert-butyl (S)-3,3-difluoro-4-hydroxypyrrolidine-1-carboxylate (CAS 1873374-41-4), a certified reference material (molecular formula C9H15F2NO3, MW 223.22 g/mol) for analytical method development and quality control.
The molecular framework of Tert-butyl (S)-3,3-difluoro-4-hydroxypyrrolidine-1-carboxylate (C9H15F2NO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Tert-butyl (S)-3,3-difluoro-4-hydroxypyrrolidine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H15F2NO3 |
| Molecular Weight | 223.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 4-(3,5-Difluorophenyl)tetrahydro-2H-pyran-4-carbonitrile (CAS 179421-07-9)
- 2-(Ethylsulfanyl)-5-(trifluoromethyl)pyridin-3-ol (CAS 1881320-39-3)
- 2-{[5-(trifluoromethyl)-2-pyridyl]thio}ethan-1-ol (CAS 173729-52-7)
- (2R,3R,4S,5S,6R)-2-(2-aminoethoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (CAS 70337-78-9)
- (4-(2-Aminoethyl)piperazin-1-yl)(3-methoxy-1-methyl-1h-pyrazol-4-yl)methanone (CAS 1204297-17-5)
- 5-[3-(Isopropylsulfonyl)phenyl]-1,3,4-oxadiazol-2-amine (CAS 1105194-09-9)
- 2-(Difluoromethyl)-6-hydroxy-4-nitronicotinic acid (CAS 1806973-57-8)
- Tert-butyl 2-(hydroxymethyl)-2-methylpiperidine-1-carboxylate (CAS 470669-15-9)
- tert-Butyl (1-(2-amino-1-(4-chlorophenyl)ethyl)pyrrolidin-3-yl)carbamate (CAS 886365-23-7)
- N-(3-Fluorophenyl)piperidin-4-amine (CAS 886506-63-4)
- Ethyl 2-(benzoylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate (CAS 52580-57-1)
- 2-Chloro-N-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]propanamide (CAS 565165-72-2)
- 2-[2-{2-(Dimethylamino)-3-[2-(1,3,3-Trimethyl-1,3-Dihydro-2H-Indol-2-Ylidene)Ethylidene]-1-Cyclohexen-1-Yl}Vinyl]-1,3,3-Trimethyl-3H-Indolium Tetrafluoroborate (CAS 246517-75-9)
- [a-Glu](Side chain transposition)- Semaglutide (CAS CATO-C4X-2226111)
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