n-(4-Amino-2-chlorophenyl)methanesulfonamide CAS 18735-42-7

Description

The occurrence of n-(4-Amino-2-chlorophenyl)methanesulfonamide is closely related to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

n-(4-Amino-2-chlorophenyl)methanesulfonamide (CAS 18735-42-7) is a high-purity analytical reference standard with the molecular formula C7H9ClN2O2S and a molecular weight of 220.68 g/mol.

n-(4-Amino-2-chlorophenyl)methanesulfonamide (C7H9ClN2O2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), n-(4-Amino-2-chlorophenyl)methanesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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