2-(2-Fluorophenyl)-4-iodoacetophenone CAS 187617-12-5

Purity 97%+In StockPharmaceutical Standards
CAS No.187617-12-5
Molecular FormulaC14H10FIO
Molecular Weight340.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(2-Fluorophenyl)-4-iodoacetophenone CAS 187617-12-5 chemical structure

Description

The molecular framework of 2-(2-Fluorophenyl)-4-iodoacetophenone (C14H10FIO) is characterized by a hydroxyl group, an ether linkage, fluorine/iodine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

2-(2-Fluorophenyl)-4-iodoacetophenone (CAS 187617-12-5) is a high-purity analytical reference standard with the molecular formula C14H10FIO and a molecular weight of 340.13 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-(2-Fluorophenyl)-4-iodoacetophenone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC14H10FIO
Molecular Weight340.13 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2010
Halogen ContentF/I-containing

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