Revefenacin Impurity 19 CAS 187741-66-8
| CAS No. | 187741-66-8 |
| Molecular Formula | C14H13NO2 |
| Molecular Weight | 227.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Revefenacin Impurity 19 (CAS 187741-66-8, C14H13NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Revefenacin Impurity 19 (C14H13NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 227.26 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H13NO2 |
| Molecular Weight | 227.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Nitrogen Atoms | 1 |
Related Revefenacin Standards
- Revefenacin impurity 75 (CAS CATO-C4X-203175)
- Revefenacin impurity 105 (CAS CATO-C4X-2031105)
- Revefenacin impurity 106 (CAS 886508-20-9)
- Revefenacin impurity 33 (CAS CATO-C4X-203133)
- Revefenacin Impurity 17 (CAS 96053-48-4)
- Revefenacin impurity 32 (CAS CATO-C4X-203132)
- Revefenacin Impurity 3 (CAS 50443-60-2)
- Revefenacin impurity 90 (CAS CATO-C4X-203190)
Recommended Standards
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