4-(Chlorocarbonyl)-2,6-dimethoxyphenyl ethyl carbonate CAS 18780-68-2

Purity 97%+In StockPharmaceutical Standards
CAS No.18780-68-2
Molecular FormulaC12H13ClO6
Molecular Weight288.68 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(Chlorocarbonyl)-2,6-dimethoxyphenyl ethyl carbonate CAS 18780-68-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Chlorocarbonyl)-2,6-dimethoxyphenyl ethyl carbonate.

4-(Chlorocarbonyl)-2,6-dimethoxyphenyl ethyl carbonate (CAS 18780-68-2) is a high-purity analytical reference standard with the molecular formula C12H13ClO6 and a molecular weight of 288.68 g/mol.

4-(Chlorocarbonyl)-2,6-dimethoxyphenyl ethyl carbonate (C12H13ClO6) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-(Chlorocarbonyl)-2,6-dimethoxyphenyl ethyl carbonate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H13ClO6
Molecular Weight288.68 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1962
Halogen ContentCl-containing

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