Amoxicillin EP Impurity G CAS 188112-75-6
| CAS No. | 188112-75-6 |
| Molecular Formula | C24H26N4O7S |
| Molecular Weight | 514.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Amoxicillin EP Impurity G meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Amoxicillin EP Impurity G (CAS 188112-75-6) is a certified pharmaceutical impurity reference standard with the molecular formula C24H26N4O7S and a molecular weight of 514.55 g/mol.
Amoxicillin EP Impurity G (C24H26N4O7S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C24H26N4O7S |
| Molecular Weight | 514.55 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Amoxicillin Standards
- Amoxicillin impurity 111 (CAS CATO-C4X-1148111)
- Amoxicillin double side chain impurity (CAS CATO-C4X-114840)
- Amoxicillin Impurity 43 (CAS CATO-C4X-114843)
- Amoxicillin Impurity 88 (CAS CATO-C4X-114888)
- Amoxicillin Impurity 38 (CAS CATO-C4X-114838)
- Amoxicillin Impurity 75 (CAS CATO-C4X-114875)
- Amoxicillin Clavulanate Potassium Dimer (CAS CATO-C4X-114865)
- Amoxicillin EP Impurity L (CAS 1789703-32-7)
Recommended Standards
- 3,6-Dimethoxypyridazin-4-amine (CAS 1075-68-9)
- Bis-PEG9-acid (CAS 1268488-70-5)
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- Etrasimod Impurity 67 (CAS CATO-C4X-321467)
- Apixaban Impurity 94 (CAS 813452-05-0)
- Bupivacaine Impurity 34 (CAS 98348-30-2)
- Samidorphan Impurity 10 (CAS 886588-56-3)
- 3(2H)-Pyridazinone, 6-(4-chlorophenyl)-, hydrazone 60478-25-3 CTK2F0328 (CAS 60478-25-3)
- 1-(6-(5-Aminopyrazin-2-yl)pyridin-3-yl)cyclobutanecarbonitrile (CAS 1369513-84-7)
- Tert-butyl 2-amino-5-oxa-8-azaspiro[3.5]Nonane-8-carboxylate (CAS 1251020-91-3)
- Ethyl 2-(4-Chlorobenzyl)oxazole-4-carboxylate (CAS 1309576-06-4)
- Fmoc-L-cyclopropylglycine (CAS 1212257-18-5)
- 1-{4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl}-2-chloroethan-1-one (CAS 937047-12-6)
- Des-[Ser]8-Liraglutide (CAS CATO-C4X-199233)
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