3,3-difluoropyrrolidine-2-carboxylic acid;hydrochloride CAS 1881265-73-1
| CAS No. | 1881265-73-1 |
| Molecular Formula | C5H7F2NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 187.57 g/mol gives 3,3-difluoropyrrolidine-2-carboxylic acid;hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3,3-difluoropyrrolidine-2-carboxylic acid;hydrochloride (CAS 1881265-73-1) is a high-purity analytical reference standard with the molecular formula C5H7F2NO2HCl and a molecular weight of 187.57 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 3,3-difluoropyrrolidine-2-carboxylic acid;hydrochloride is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 187.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3,3-difluoropyrrolidine-2-carboxylic acid;hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H7F2NO2 HCl |
| Molecular Weight | 187.57 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related difluoropyrrolidine Standards
- 4,4-difluoropyrrolidine-2-carboxylic acid (CAS 1073555-68-6)
- 3,4-Difluoropyrrolidine (CAS 1144062-04-3)
- 3,3-Difluoropyrrolidine-1-sulfonyl chloride (CAS 1187160-31-1)
- Ethyl 4,4-difluoropyrrolidine-3-carboxylate (CAS 1258650-97-3)
- (R)-4,4-difluoropyrrolidine-2-carboxamide (CAS 1315304-75-6)
- 3,3-Difluoropyrrolidine-1-carbonyl chloride (CAS 1334512-01-4)
- 4,4-Difluoropyrrolidine-2-carboxylicacidhydrochloride (CAS 1354949-90-8)
- (S)-4,4-Difluoropyrrolidine-2-carbaldehyde (CAS 1357281-62-9)
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- 2-(4-Oxo-2-thioxo-3-thiazolidinyl)butanedioic acid (CAS 31316-80-0)
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- (3R)-1-(trideuteriomethyl)pyrrolidin-3-amine (CAS 2694068-62-5)
- 2-[(3,5-Dinitrobenzoyl)amino]-2-phenyl-acetic acid (CAS 74958-71-7)
- Acetyl Tetrapeptide- 15 (CAS 928007-64-1)
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