3-Butoxy-4-fluoro-5-(trifluoromethyl)phenol CAS 1881288-72-7
| CAS No. | 1881288-72-7 |
| Molecular Formula | C11H12F4O2 |
| Molecular Weight | 252.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-Butoxy-4-fluoro-5-(trifluoromethyl)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-Butoxy-4-fluoro-5-(trifluoromethyl)phenol (CAS 1881288-72-7), molecular formula C11H12F4O2 and molecular weight 252.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Butoxy-4-fluoro-5-(trifluoromethyl)phenol (C11H12F4O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12F4O2 |
| Molecular Weight | 252.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
Related Butoxy Standards
- 3-(2-(tert-Butoxy)-2-oxoethoxy)benzoic acid (CAS 313709-63-6)
- 5-((2-(tert-Butoxy)-2-oxoethyl)amino)picolinic acid (CAS 112888-56-9)
- 3-(tert-Butoxy)-5-cyclopropoxy-2-nitropyridine (CAS 1243284-24-3)
- 2-(tert-Butoxy)-4-cyclopropoxy-3-nitropyridine (CAS 1243286-38-5)
- 5-(tert-Butoxy)-3-cyclopropoxy-2-nitropyridine (CAS 1243346-56-6)
- 5-(tert-Butoxy)-4-cyclopropoxy-2-nitropyridine (CAS 1243362-88-0)
- 2-(tert-Butoxy)-4-cyclopropoxy-6-nitropyridine (CAS 1243372-90-8)
- 3-(tert-Butoxy)-5-cyclopropoxy-4-nitropyridine (CAS 1243374-48-2)
Recommended Standards
- 4-(3-Bromopropyl)-2,2-dimethylthiomorpholine (CAS 1600014-70-7)
- 2-(Ethylsulfanyl)-3-nitro-5-(trifluoromethyl)pyridine (CAS 1881332-14-4)
- 1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-methylpropan-2-ol (CAS 1443330-64-0)
- (2-azido-3-pyridyl)-pentafluoro-sulfane (CAS 1982380-93-7)
- 1,1-Dioxido-3,6-dihydro-2H-thiopyran-4-boronic Acid Pinacol Ester (CAS 1370535-33-3)
- 1-Isopropyl-3-methyl-1H-pyrazol-5-amine (CAS 1124-16-9)
- (R)-5-bromo-2-(pyrrolidin-3-yloxy)pyridine hydrochloride (CAS 1417789-14-0)
- 1,5-Dichloro-3-iodo-2-methylbenzene (CAS 1215795-58-6)
- 4-(((6-(3,5-Dimethyl-1H-pyrazol-1-yl)pyridazin-3-yl)thio)methyl)-2-methylthiazole (CAS 1351631-85-0)
- n-(4-Carbamothioylphenyl)propanamide (CAS 950094-51-6)
- 5-[5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl]pyridin-2-amine (CAS 2086260-68-4)
- N-(4-(benzyloxy)phenyl)-2-cyanoacetamide (CAS 524036-03-1)
- Acetylcysteine Impurity 50 (CAS 24125-26-6)
- Semaglutide impurity 277 (CAS CATO-C4X-2226277)
Why CATO?
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