tert-Butyl 5-[(tert-butyldimethylsilyl)oxy]-2-nitro-1H-indole-1-carboxylate CAS 1881289-36-6
| CAS No. | 1881289-36-6 |
| Molecular Formula | C19H28N2O5Si |
| Molecular Weight | 392.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of tert-Butyl 5-[(tert-butyldimethylsilyl)oxy]-2-nitro-1H-indole-1-carboxylate (C19H28N2O5Si) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
tert-Butyl 5-[(tert-butyldimethylsilyl)oxy]-2-nitro-1H-indole-1-carboxylate (CAS 1881289-36-6), molecular formula C19H28N2O5Si and molecular weight 392.52 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H28N2O5Si |
| Molecular Weight | 392.52 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 2 |
Recommended Standards
- N-(Thiophen-2-ylmethyl)-1-(6-(o-tolyl)pyridazin-3-yl)piperidine-4-carboxamide (CAS 1105232-97-0)
- 2-((1H-1,2,4-Triazol-5-yl)thio)-1-(2,2,4-trimethyl-4-phenyl-3,4-dihydroquinolin-1(2H)-yl)ethan-1-one (CAS 298204-30-5)
- Exemestane Impurity 11 (CAS CATO-C4X-164111)
- 2-((3-Allyl-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)-N-(thiazol-2-yl)acetamide (CAS 501112-75-0)
- N-Ethyl-2-methoxy-5-nitropyridin-4-amine (CAS 607373-90-0)
- 3,3-Dimethyl-5-propionylindolin-2-one (CAS 120476-85-9)
- (R)-3-(fluoromethyl)-1-methylpiperazine (CAS 2387560-48-5)
- 2-Phenyl-1H-benzo[d]imidazol-5-ol hydrobromide (CAS 1051369-19-7)
- Benzyl 3-sulfamoylpiperidine-1-carboxylate (CAS 2146077-43-0)
- 10-Hydroxy desipramine, >98% (CAS 4014-82-8)
- 1,1,1,3,3,3-Hexafluoro-2-phenylpropan-2-yl methacrylate (CAS 130540-87-3)
- Methyl 2-bromo-4-cyano-6-formylbenzoate (CAS 1805247-31-7)
- 5-Bromo-6-fluoro-1-benzofuran (CAS 1427417-54-6)
- Cholecystokinin Octapeptide (1-3) (desulfated) H-Asp-Tyr-Met-OH (CAS 121880-94-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com