tert-Butyl(6-chloro-2-fluoro-3-nitrophenoxy)dimethylsilane CAS 1881329-20-9
| CAS No. | 1881329-20-9 |
| Molecular Formula | C12H17ClFNO3Si |
| Molecular Weight | 305.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 305.81 g/mol gives tert-Butyl(6-chloro-2-fluoro-3-nitrophenoxy)dimethylsilane distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
tert-Butyl(6-chloro-2-fluoro-3-nitrophenoxy)dimethylsilane (CAS 1881329-20-9), molecular formula C12H17ClFNO3Si and molecular weight 305.81 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, tert-Butyl(6-chloro-2-fluoro-3-nitrophenoxy)dimethylsilane is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 305.81 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), tert-Butyl(6-chloro-2-fluoro-3-nitrophenoxy)dimethylsilane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H17ClFNO3Si |
| Molecular Weight | 305.81 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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