1-[(3-Chloro-5-fluorophenyl)carbonyl]piperidine CAS 1881330-71-7

Description

The occurrence of 1-[(3-Chloro-5-fluorophenyl)carbonyl]piperidine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1-[(3-Chloro-5-fluorophenyl)carbonyl]piperidine (CAS 1881330-71-7), molecular formula C12H13ClFNO and molecular weight 241.69 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 1-[(3-Chloro-5-fluorophenyl)carbonyl]piperidine is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 241.69 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1-[(3-Chloro-5-fluorophenyl)carbonyl]piperidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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