3-Chloro-2,6-difluoropyridine hydrate CAS 1881331-11-8
| CAS No. | 1881331-11-8 |
| Molecular Formula | C5H2ClF2N |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Chloro-2,6-difluoropyridine hydrate.
3-Chloro-2,6-difluoropyridine hydrate (CAS 1881331-11-8), molecular formula C5H2ClF2NH2O and molecular weight 167.54 g/mol, is a CATO reference standard with documented purity and traceability.
3-Chloro-2,6-difluoropyridine hydrate (C5H2ClF2NH2O) contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Chloro-2,6-difluoropyridine hydrate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H2ClF2N H2O |
| Molecular Weight | 167.54 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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- 6-Morpholino-2-phenyl-1H-benzo[de]isoquinoline-1,3(2H)-dione (CAS 87223-13-0)
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- N-butyl-N-(prop-2-yn-1-yl)butan-1-amine (CAS 6336-58-9)
- Liraglutide Impurity 14 TFA Salt (CAS CATO-C4X-199214)
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