rel-(4R,4′R)-4,4′,5,5′-Tetrahydro-4,4′-bis(phenylmethyl)-2,2′-bioxazole CAS 188255-29-0
| CAS No. | 188255-29-0 |
| Molecular Formula | C20H20N2O2 |
| Molecular Weight | 320.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
rel-(4R,4′R)-4,4′,5,5′-Tetrahydro-4,4′-bis(phenylmethyl)-2,2′-bioxazole (CAS 188255-29-0), molecular formula C20H20N2O2 and molecular weight 320.39 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of rel-(4R,4′R)-4,4′,5,5′-Tetrahydro-4,4′-bis(phenylmethyl)-2,2′-bioxazole (C20H20N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), rel-(4R,4′R)-4,4′,5,5′-Tetrahydro-4,4′-bis(phenylmethyl)-2,2′-bioxazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H20N2O2 |
| Molecular Weight | 320.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Nitrogen Atoms | 2 |
Recommended Standards
- tert-Butyl 4-{4-[amino(hydroxyimino)methyl]-phenyl}tetrahydro-1(2H)-pyrazinecarboxylate (CAS 186650-24-8)
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- Benzyl spiro[indole-3,4'-piperidine]-1'-carboxylate (CAS 184289-85-8)
- 5-(Benzyloxy)-4-methoxy-N1-phenylbenzene-1,2-diamine (CAS 1923069-45-7)
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- Imidazo[1,2-a]pyridine-5-carboxaldehyde, 2-methyl- (CAS 1042981-20-3)
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- (3-Fluoro-5-((4-methoxybenzyl)carbamoyl)phenyl)boronic acid (CAS 1704082-30-3)
- 1-(2-Methylpyrimidin-4-yl)piperidin-4-amine (CAS 1329748-51-7)
- Diethyl 3,3'-(propylazanediyl)dipropionate (CAS 3619-65-6)
- 1-Phenyl-3-(2-((tetrahydro-2H-pyran-4-yl)thio)ethyl)urea (CAS 1795191-13-7)
- tert-butyl N-(2-cyclopropyl-1,3-thiazol-4-yl)carbamate (CAS 1823503-36-1)
- tert-Butyl 2-((tert-butoxycarbonyl)amino)-1H-imidazole-1-carboxylate (CAS 1186299-71-7)
- Semaglutide impurity 37 (CAS CATO-C4X-222637)
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