5-Isopropyl-2-oxo-1,3-dioxole-4-carboxylic acid CAS 188525-84-0
| CAS No. | 188525-84-0 |
| Molecular Formula | C7H8O5 |
| Molecular Weight | 172.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-Isopropyl-2-oxo-1,3-dioxole-4-carboxylic acid (C7H8O5) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
5-Isopropyl-2-oxo-1,3-dioxole-4-carboxylic acid (CAS 188525-84-0) is a high-purity analytical reference standard with the molecular formula C7H8O5 and a molecular weight of 172.14 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8O5 |
| Molecular Weight | 172.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
Related Isopropyl Standards
- 5-Isopropyl-1,2,3-thiadiazole-4-carboxylic acid (CAS 1445950-78-6)
- Methyl 2-isopropyl-3,3-dimethyloxirane-2-carboxylate (CAS 1510934-60-7)
- 2-Isopropyl-5-oxohexanoic acid (CAS 2543-54-6)
- Ethyl 3-isopropyl-3-methyloxirane-2-carboxylate (CAS 274689-93-9)
- Isopropyl piperazine-1-carboxylate (CAS 37038-26-9)
- Trans-2-isopropyl-5-propyl-1,3-dioxane (CAS 19476-83-6)
- 2-Isopropyl-5-methylhexanoic acid (CAS 4384-07-0)
- N1-isopropyl-N1-methyl-N2-(oxetan-3-yl)ethane-1,2-diamine (CAS 1343119-69-6)
Recommended Standards
- (4-Fluorophenyl)dimethylphosphine oxide (CAS 18437-74-6)
- 2-Oxo-5-propyl-1,3-dioxole-4-carboxylic acid (CAS 188525-95-3)
- <I>N</I>-Succinimidyl<I>N</I>-methylcarbamate (CAS 18342-66-0)
- 5-Formyl-6-methylpyrazine-2,3-dicarbonitrile (CAS 192933-54-3)
- 3-Tert-butyl-1-ethyl-1h-pyrazol-5-amine (CAS 874136-24-0)
- (4S)-2-(3,3-dimethyloxiran-2-yl)-4-methyloxane (CAS 1604729-40-9)
- 3-(Palmitoyloxy)-2-((10-(pyren-1-yl)decanoyl)oxy)propyl (2-(trimethylammonio)ethyl) phosphate (CAS 70700-33-3)
- (2-Chloro-5-fluoropyrimidin-4-yl)-(3-trifluoromethylphenyl)amine (CAS 575473-62-0)
- 2-[2-(4-Ethylpiperazin-1-yl)ethyl]-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one (CAS 860611-75-2)
- 7-Amino-3-phenylpyrazolo[1,5-a]pyrimidine-6-carbonitrile (CAS 767346-79-2)
- 1H-Indazole-1,7-diol (CAS 877472-73-6)
- Methyl trans-3-Aminobicyclo[2.2.2]octane-2-carboxylate (CAS 65641-66-9)
- Methyl 2-methyl-3-oxo-3-(tetrahydrofuran-3-yl)propanoate (CAS 1466081-67-3)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
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