Temozolomide Impurity 3 CAS 188612-53-5
| CAS No. | 188612-53-5 |
| Molecular Formula | C6H9N5O2 |
| Molecular Weight | 183.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Temozolomide Impurity 3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Temozolomide Impurity 3 (CAS 188612-53-5) is a certified pharmaceutical impurity reference standard with the molecular formula C6H9N5O2 and a molecular weight of 183.17 g/mol.
Temozolomide Impurity 3 (C6H9N5O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C6H9N5O2 |
| Molecular Weight | 183.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Nitrogen Atoms | 5 |
Related Temozolomide Standards
- Temozolomide Impurity 19 (CAS CATO-C4X-135319)
- Temozolomide EP Impurity C (CAS 114601-31-9)
- Temozolomide EP Impurity B (CAS 113942-30-6)
- Temozolomide Metabolite-MTIC-d3 (CAS 1185242-69-6)
- Temozolomide-d3 (CAS 208107-14-6)
- Temozolomide Metabolite-MTIC (CAS 1232679-46-7)
- Temozolomide Impurity 4 (CAS 3413-72-7)
- Temozolomide Impurity 17 (CAS CATO-C4X-135317)
Recommended Standards
- Theophylline Impurity 14 (CAS CATO-C4X-182314)
- 4-Methyl-6-(trifluoromethyl)pyrimidin-2-amine 5734-63-4 8429AB C6H6F3N3 (CAS 5734-63-4)
- N-Nitroso Theophylline EP Impurity D (CAS CATO-C4X-18238)
- 42072-27-5 O,O-Dimethyl acetylthiophosphoramidate Phosphoramidothioic acid, N-acetyl-, O,O-dimethyl ester Phosphoramidothioic acid, acetyl-, O,O-dimethyl ester EINECS 255-646-8 (CAS 42072-27-5)
- Ixazomib Impurity 55 (CAS CATO-C4X-126755)
- Benzbromarone EP Impurity C (CAS 1477-19-6)
- Rabeprazole Impurity 25 (CAS 1286104-27-5)
- 2-Isobutoxy-4-methyl-1-nitrobenzene (CAS 640767-54-0)
- 2-Chloro-N-[(4-chlorophenyl)methyl]aniline (CAS 13159-72-3)
- Z-D-allo-Thr(tBu)-OH · DCHA (CAS 100157-55-9)
- tert-Butyl methyl(1-methylazetidin-3-yl)carbamate (CAS 1379306-73-6)
- 3-amino-5-chloro-1-methyl-1,2-dihydropyridin-2-one (CAS 1441769-24-9)
- 3-[4-[3-(2-hydroxyethoxy)propyl]-1-oxo-isoindolin-2-yl]piperidine-2,6-dione (CAS 2599845-88-0)
- Allo-D-Ile27-Tirzepatide (CAS CATO-CPTD788961)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com