1-(4-(Trifluoromethyl)phenyl)pyrrolidin-2-one CAS 188622-31-3
| CAS No. | 188622-31-3 |
| Molecular Formula | C11H10F3NO |
| Molecular Weight | 229.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(4-(Trifluoromethyl)phenyl)pyrrolidin-2-one (CAS 188622-31-3) is a high-purity analytical reference standard with the molecular formula C11H10F3NO and a molecular weight of 229.20 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 1-(4-(Trifluoromethyl)phenyl)pyrrolidin-2-one is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 229.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 1-(4-(Trifluoromethyl)phenyl)pyrrolidin-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10F3NO |
| Molecular Weight | 229.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 3-(3-(Trifluoromethyl)-5,6-dihydrocyclopenta[c]pyrazol-1(4h)-yl)propanenitrile (CAS 1011371-14-4)
- 4-(2-(Trifluoromethyl)phenoxy)butanenitrile (CAS 1016821-74-1)
- 1-Ethyl-2-(trifluoromethyl)-1H-benzo[d]imidazol-5-amine (CAS 1019108-00-9)
- 4-(3-(Trifluoromethyl)phenoxy)butanenitrile (CAS 1019443-44-7)
- 1-Phenyl-5-(trifluoromethyl)pyrrolidin-2-one (CAS 1020717-92-3)
- 4-[2-(Trifluoromethyl)phenyl]-2-pyrrolidinone (CAS 1020718-46-0)
- 1-(4-(Trifluoromethyl)phenyl)pyrrolidin-3-one (CAS 1096301-15-3)
- N-{[3-(trifluoromethyl)phenyl]methyl}prop-2-enamide (CAS 1155979-78-4)
Recommended Standards
- 2-Fluoro-4-methoxy-1-nitro-3-(propan-2-yloxy)benzene (CAS 1881322-36-6)
- Methyl({[5-(trifluoromethyl)-1H-1,3-benzodiazol-2-yl]methyl})amine (CAS 193534-29-1)
- 3,3-Dimethyl-4-(trifluoromethyl)indolin-2-one (CAS 1822816-54-5)
- N-(2,3-Dihydro-1H-inden-2-yl)-2,2,2-trifluoroacetamide, 97% (CAS 193756-44-4)
- 3-Fluoro-2-iodo-6-(trifluoromethyl)pyridine (CAS 1214359-56-4)
- 2-Hydrazinyl-4-(4-methoxy-3-methylphenyl)thiazole (CAS 886494-19-5)
- (2E)-3-(4-tert-Butylphenyl)-1-(3-chlorophenyl)prop-2-en-1-one (CAS 1354941-39-1)
- 5-Methoxy-6-phenylpyridazin-3-ol (CAS 473934-58-6)
- Brimonidine Impurity 13 (CAS 134892-42-5)
- (R)-3-(Cbz-amino)-3-phenyl-1-propanol (CAS 888298-05-3)
- Orlistat Impurity 2 (CAS 104872-28-8)
- Ethyl 4-(chloromethyl)-2-((3-methoxypropyl)imino)-2,3-dihydrothiazole-5-carboxylate (CAS 937598-24-8)
- 4-Fluoro-N-pentylbenzamide (CAS 330469-24-4)
- Semaglutide Impurity 75 (CAS CATO-C4X-2226175)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com