tert-Butyl(2,5-dichlorophenoxy)dimethylsilane CAS 188645-79-6

Purity 97%+In StockPharmaceutical Standards
CAS No.188645-79-6
Molecular FormulaC12H18Cl2OSi
Molecular Weight277.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl(2,5-dichlorophenoxy)dimethylsilane CAS 188645-79-6 chemical structure

Description

The occurrence of tert-Butyl(2,5-dichlorophenoxy)dimethylsilane is closely related to a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

tert-Butyl(2,5-dichlorophenoxy)dimethylsilane (CAS 188645-79-6), molecular formula C12H18Cl2OSi and molecular weight 277.26 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, tert-Butyl(2,5-dichlorophenoxy)dimethylsilane (C12H18Cl2OSi) contains a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 277.26 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H18Cl2OSi
Molecular Weight277.26 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)2010
Halogen ContentCl-containing

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