5-Chloro-1-ethyl-3-(trifluoromethyl)-1H-pyrazol-4-amine CAS 188689-57-8
| CAS No. | 188689-57-8 |
| Molecular Formula | C6H7ClF3N3 |
| Molecular Weight | 213.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Chloro-1-ethyl-3-(trifluoromethyl)-1H-pyrazol-4-amine (CAS 188689-57-8), molecular formula C6H7ClF3N3 and molecular weight 213.59 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C6H7ClF3N3, 5-Chloro-1-ethyl-3-(trifluoromethyl)-1H-pyrazol-4-amine contains a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 213.59 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 5-Chloro-1-ethyl-3-(trifluoromethyl)-1H-pyrazol-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H7ClF3N3 |
| Molecular Weight | 213.59 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 2-[4-chloro-3-(trifluoromethyl)-1h-pyrazol-1-yl]ethan-1-amine (CAS 1006473-61-5)
- 7-Chloro-5-fluoro-1H-indole-2-carboxylic acid (CAS 1126084-31-8)
- 7-Chloro-4-fluoro-1H-indole-2-carboxylic acid (CAS 1158593-32-8)
- 5-Chloro-6-fluoro-3-hydroxyquinolin-2(1H)-one (CAS 1159706-41-8)
- Methyl 2-chloro-4-cyano-6-fluorobenzoate (CAS 1258298-28-0)
- 3-Chloro-6-fluoro-1H-indole-2-carboxylic acid (CAS 1312138-48-9)
- 3-Chloro-4-fluoro-1H-indole-2-carboxylic acid (CAS 1312138-70-7)
- 4-Chloro-1-(3,3,3-trifluoropropyl)-1h-pyrazol-3-amine (CAS 1343188-88-4)
Recommended Standards
- 6-Chloro-4-fluoro-1H-indole-2-carboxylic acid (CAS 186446-27-5)
- 2-chloro-4-(difluoromethyl)-1,3-thiazole-5-carboxylic acid (CAS 2060029-60-7)
- 5-Chloro-4-fluoro-1h-indole-2-carboxylicacid (CAS 186446-26-4)
- 3-chloro-5-fluoro-1H-indole-2-carboxylic acid (CAS 480450-96-2)
- Ethyl 2-oxocyclobutane-1-carboxylate (CAS 213478-56-9)
- (S,R,S)-AHPC-CO-C10-acid (CAS 2357115-09-2)
- (1s)-1-(4-Ethoxyphenyl)ethan-1-ol (CAS 116071-56-8)
- (E)-3-((2-(3-chlorophenyl)hydrazono)methyl)-4-hydroxy-6-methyl-2H-pyran-2-one (CAS 477868-39-6)
- 1-Boc-5-bromo-1H-pyrazolo[3,4-b]pyridine (CAS 1299607-55-8)
- 2-Methylthiazolidine-4-carboxylic Acid (CAS 4165-32-6)
- 3-((2,4-Dichlorobenzyl)thio)-4-methyl-5-(2-methylfuran-3-yl)-4H-1,2,4-triazole (CAS 849125-00-4)
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- (3-Fluoro-4-((2-fluorophenyl)carbamoyl)phenyl)boronic acid (CAS 2096332-65-7)
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