5-Chloro-6-(naphthalen-1-ylamino)pyrazine-2,3-dicarbonitrile CAS 188710-69-2
| CAS No. | 188710-69-2 |
| Molecular Formula | C16H8ClN5 |
| Molecular Weight | 305.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-Chloro-6-(naphthalen-1-ylamino)pyrazine-2,3-dicarbonitrile (C16H8ClN5) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
5-Chloro-6-(naphthalen-1-ylamino)pyrazine-2,3-dicarbonitrile (CAS 188710-69-2), molecular formula C16H8ClN5 and molecular weight 305.72 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H8ClN5 |
| Molecular Weight | 305.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
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Recommended Standards
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- Chlorhexidine Impurity 31 (CAS CATO-C4X-225631)
- Formoterol Impurity 67 (CAS 871266-45-4)
- 3-Hydroxy-2-(4-methoxyphenyl)quinazolin-4(3H)-one (CAS 83583-77-1)
- 2-methyl-3-(piperidin-2-yl)propanoic acid hydrochloride (CAS 1909336-01-1)
- (1R*,4R*)-4-(5-Aminopyridin-2-ylamino)cyclohexanol (CAS 1233955-56-0)
- 3-(Aminomethyl)-6-phenyl-1,2-dihydropyridin-2-one (CAS 1248701-76-9)
- 3-(bromomethyl)-2-chlorothiophene 1-oxide (CAS CATO-C4X-25473)
- Cholane Related Compoumd 1 (5-alpha-Homopregnanic Acid) (CAS 34311-19-8)
- (2,4-Dichloro-6-hydroxyphenyl)boronic acid (CAS 1028332-22-0)
- 3-(4-Isopropylphenyl)-3-methylbutan-1-amine (CAS 1226413-50-8)
- Methyl cyclobut-2-ene-1-carboxylate (CAS 15963-45-8)
- Galanin Message Associated Peptide (44-59) amide (CAS 125455-59-6)
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