6-Bromo-4-methyl-1H-indole-2-carboxylic acid CAS 18873-97-7
| CAS No. | 18873-97-7 |
| Molecular Formula | C10H8BrNO2 |
| Molecular Weight | 254.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Bromo-4-methyl-1H-indole-2-carboxylic acid (CAS 18873-97-7) is a high-purity analytical reference standard with the molecular formula C10H8BrNO2 and a molecular weight of 254.08 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, 6-Bromo-4-methyl-1H-indole-2-carboxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 254.08 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8BrNO2 |
| Molecular Weight | 254.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-(7-Bromo-1H-indol-2-yl)acetic acid (CAS 1018591-46-2)
- 2-(6-Bromo-1H-indol-2-yl)acetic acid (CAS 1018635-71-6)
- 2-Bromo-6-(furan-2-ylmethoxy)pyridine (CAS 1065484-89-0)
- 1-Acetyl-5-bromo-2H-indol-3-one (CAS 106698-07-1)
- Methyl 3-Bromo-4-(cyanomethyl)benzoate (CAS 1069114-89-1)
- 3-(5-Bromo-2-methoxyphenyl)-3-oxopropanenitrile (CAS 1071398-50-9)
- Methyl 6-bromo-4-indolecarboxylate (CAS 107650-22-6)
- 5-Bromo-2-methyl-1H-indole-3-carboxylic acid (CAS 1082572-35-7)
Recommended Standards
- 4-Bromo-5-methyl-1H-indole-2-carboxylic acid (CAS 1857357-32-4)
- 5-(2-Bromophenyl)pyrrolidine-2,4-dione (CAS 1889412-61-6)
- 3-Bromo-5-fluorobenzene-1-sulfonamide (CAS 1843194-48-8)
- 2-(2-Bromo-1H-indol-3-yl)acetic acid (CAS 1912-39-6)
- L-Glutamic Acid (CAS 56-86-0)
- 2,3-Dioxononanoic acid (CAS 5281-09-4)
- 4-Bromo-5-isopropyl-3-methyl-1H-pyrazole (CAS 60061-69-0)
- 3-Phenylisoquinolin-4-ol (CAS 51787-73-6)
- Halowax 1014 (CAS 1335-87-1)
- N,N,4,4,5,5-Hexamethyl-1,3,2-dioxaborolan-2-amine (CAS 557087-01-1)
- Ethyl 3-(4-bromopyridin-2-yl)-2-oxopropanoate (CAS 2140305-33-3)
- Tert-butyl(3-ethynyl-4-fluorophenoxy)dimethylsilane (CAS 2187435-17-0)
- 4'-Methyl-5,6-dihydro-[1,1'-biphenyl]-3(4H)-one (CAS 6330-12-7)
- [His]1-Acetylated Semaglutide (CAS CATO-C4X-2226219)
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