4-(Chlorodifluoromethyl)pyrimidine-5-carboxamide CAS 188740-00-3
| CAS No. | 188740-00-3 |
| Molecular Formula | C6H4ClF2N3O |
| Molecular Weight | 207.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(Chlorodifluoromethyl)pyrimidine-5-carboxamide is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(Chlorodifluoromethyl)pyrimidine-5-carboxamide (CAS 188740-00-3), molecular formula C6H4ClF2N3O and molecular weight 207.57 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C6H4ClF2N3O, 4-(Chlorodifluoromethyl)pyrimidine-5-carboxamide contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 207.57 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-(Chlorodifluoromethyl)pyrimidine-5-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4ClF2N3O |
| Molecular Weight | 207.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorodifluoromethyl Standards
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Recommended Standards
- 6-Chloro-2,2-difluorobenzo[d][1,3]dioxol-5-amine (CAS 73051-44-2)
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- 3-Chloro-5-(trifluoromethyl)-2-vinylpyridine (CAS 1512811-14-1)
- 4-Amino-5-chloro-2,3-difluorobenzoic acid (CAS 2649788-84-9)
- (αR)-Hydroxy-benzenebutanoic Acid tert-Butyl Ester (CAS 138333-11-6)
- 4-(Pyridin-2-ylmethyl)piperazin-1-amine (CAS 1338494-54-4)
- 4-(Difluoromethyl)-3-methylpyridin-2(1H)-one (CAS 1804486-05-2)
- 2-(Fluoromethyl)pyrrolidine hydrochloride (CAS 1781050-17-6)
- 5-(Hydroxymethyl)-1H-1,2,4-triazole-3(2H)-thione (CAS 221524-72-7)
- 1-Benzyl-2,3-dihydro-1h-indole-5-carbaldehyde (CAS 63263-84-3)
- Rel-2,2,2-trifluoro-N-((3R,4R)-4-methylpiperidin-3-yl)acetamide (CAS 2048228-00-6)
- 2,3-Dibromoimidazo[1,2-a]pyridine (CAS 1333222-44-8)
- 1-(4-Fluoro-2-methylphenyl)-4-hydroxy-1h-pyrazole-3-carboxylic acid (CAS 1152602-54-4)
- Mast Cell Degranulating (MCD) Peptide (CAS 32908-73-9)
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