Lurasidone Impurity 21 CAS 188797-79-7
| CAS No. | 188797-79-7 |
| Molecular Formula | C14H18ClN3O |
| Molecular Weight | 279.77 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Lurasidone Impurity 21 (C14H18ClN3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 279.77 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Lurasidone Impurity 21 (CAS 188797-79-7, C14H18ClN3O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H18ClN3O |
| Molecular Weight | 279.77 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Lurasidone Standards
- Lurasidone Impurity 51 (CAS 2190680-18-1)
- Lurasidone Impurity 55 (CAS CATO-C4X-102855)
- Lurasidone Impurity 40 (CAS 186204-35-3)
- Lurasidone Impurity 56 (CAS 173658-50-9)
- Lurasidone Impurity 20 (CAS CATO-C4X-102820)
- Lurasidone Impurity 37 (CAS CATO-C4X-102837)
- Lurasidone Impurity 38 (CAS 55745-83-0)
- Lurasidone Impurity 24 (CAS 1260138-03-1)
Recommended Standards
- 5-(Benzo[d]thiazol-2-yl)thiophene-2-carbonyl chloride (CAS 1706462-04-5)
- 1-(4-Chlorobenzyl)-N3,N3,N5,N5-tetramethyl-1H-1,2,4-triazole-3,5-diamine (CAS 338748-18-8)
- 7'-Chloro-1'-ethyl-1'H-spiro[piperidine-4,2'-quinazolin]-4'(3'H)-one (CAS 1325304-52-6)
- 2-Chloro-n-(3-cyano-1-cyclopentyl-4,5-dimethyl-1h-pyrrol-2-yl)acetamide (CAS 923190-03-8)
- Sildenafil Impurity 303 (CAS CATO-C4X-1128303)
- Lidocaine Impurity 93 (CAS CATO-C4X-167993)
- Metformin Impurity 35 (CAS 7260-94-8)
- Noradrenaline(Norepinephrine) Impurity 68 (CAS 67083-58-3)
- 3-(Bromomethyl)decane (CAS 1489133-88-1)
- methyl 4-cyano-1H-indole-6-carboxylate (CAS 885518-38-7)
- 1-(2-Chloro-8-isopropylquinolin-3-yl)ethanone (CAS 1017463-88-5)
- 1-(7-Chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)ethan-1-one (CAS 2387601-56-9)
- 2-Methyl-4-(3-pyridyl)thiazole (CAS 122845-35-6)
- Glu17-Semaglutide (CAS CATO-C4X-2226209)
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